Sökning: "hemithioacetal formation"

Hittade 2 avhandlingar innehållade orden hemithioacetal formation.

1. 1. Dynamic Sulfur Chemistry : Screening, Evaluation and Catalysis

   Författare :Rémi Caraballo; Olof Ramström; Nicolas Giuseppone; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Dynamic combinatorial chemistry; dynamic sulfur chemistry; thioglycoside; mutarotation; disulfide metathesis; hemithioacetal formation; 1H STD-NMR; inhibition; phosphine; Concanavalin A; beta-galactosidase; dynamic drug discovery.; Chemistry; Kemi; Organic chemistry; Organisk kemi; Bioorganic chemistry; Bioorganisk kemi;

   Sammanfattning : This thesis deals with the design, formation and evaluation of dynamic systems constructed by means of sulfur-containing reversible reactions, in organic and aqueous media and under mild conditions. In a first part, the synthesis of thioglycoside derivatives, constituting the biologically relevant starting components of the dynamic systems, is described. LÄS MER

3. 2. Discovery-Oriented Screening of Dynamic Systems: Combinatorial and Synthetic Applications

   Författare :Marcus Angelin; Olof Ramström; Stefan Kubik; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; chemical education; crystallization; dynamic combinatorial chemistry; dynamic combinatorial resolution; dynamic system; enzyme catalysis; isoindolinone; lipase; nitroalcohol; nitroaldol reaction; phthalide; reversible; secondary alcohol; systems chemistry; tandem reaction; Organic chemistry; Organisk kemi; Bioorganic chemistry; Bioorganisk kemi;

   Sammanfattning : This thesis is divided into six parts, all centered around the development of dynamic (i.e., reversibly interacting) systems of molecules and their applications in dynamic combinatorial chemistry (DCC) and organic synthesis. LÄS MER