Sökning: "hematologic malignancy"

Hittade 5 avhandlingar innehållade orden hematologic malignancy.

  1. 1. Health hazards and cancer in relation to occupational exposures among Swedish seafarers

    Författare :Karl Forsell; Eva Andersson; Ingrid Liljelind; Bengt Järvholm; Bente Moen; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; seafarer; work environment; mesothelioma; lung cancer; hematologic malignancy; benzene; epidemiologi; Epidemiology; Toxicology; toxikologi; family medicine; allmänmedicin; seafarer; work environment; mesothelioma; lung cancer; hematologic malignancy; benzene;

    Sammanfattning : This thesis explores health hazards for seafarers in the Swedish merchant fleet, and occupational risks for lung cancer, mesothelioma and hematologic malignancy (HM). A special focus has been exposure to benzene and biomarker levels for work on product or chemical tankers during the mid-1990’ies. LÄS MER

  3. 2. Molecular properties of serum thymidine kinase 1 and use of the canine enzyme in disease monitoring

    Författare :Hanan Sharif; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Thymidine kinase 1 (ATP: thymidine 5'-phosphotransferase, EC 2.7.1.21, TK1) catalyzes the transfer of the gamma phosphate group from a phosphate donor to the 5´- hydroxyl group of thymidine to form thymidine monophosphate, which is converted to thymidine triphosphate and then utilized in DNA synthesis. LÄS MER

  4. 3. Childhood overweight and pubertal timing as predictors of adult cancer in men

    Författare :Jimmy Célind; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; childhood body mass index; young adult body mass index; cancer; epidemiology; birthweight; secular trends;

    Sammanfattning : Background and Aim Obesity is one of the leading causes of cancer globally. The importance of overweight in childhood for adult cancer risk, independent of overweight status in young adulthood is still unknown. Furthermore, how male pubertal timing influences the risk of prostate cancer has not been established. LÄS MER

  5. 4. Identification and characterization of DNA sequence variants associated with multiple myeloma

    Författare :Mina Ali; Avdelningen för hematologi och transfusionsmedicin; []
    Nyckelord :Multiple myeloma; inherited susceptibility; genome-wide association study; ELL2; expression quantitative trait loci;

    Sammanfattning : Multiple myeloma (MM) is the second most common hematologic malignancy. The disease is characterized by an uncontrolled growth of malignant plasma cells in the bone marrow, producing a monoclonal immunoglobulin (“M protein”) that can be detected in peripheral blood. LÄS MER

  7. 5. Proteasome inhibition in the regulation of natural killer cell function and multiple myeloma cell apoptosis

    Författare :Xiaoli Feng; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple myeloma (MM) is a hematologic malignancy mostly occurring in the elderly and characterized by an expansion of monoclonal plasma cells in the bone marrow and increased monoclonal immunoglobulin in plasma. The outcome of this disease has been greatly improved due to introduction of new drugs. LÄS MER