Sökning: "heart defect"

Visar resultat 21 - 25 av 41 avhandlingar innehållade orden heart defect.

  1. 21. T-vector and T-loop morphology analysis of ventricular repolarization in ischemic heart disease

    Författare :Aigars Rubulis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Sudden cardiac death (SCD) is responsible for about half of all cardiovascular deaths in the western world. Heterogeneous ventricular repolarization (VR) is a common denominator in the genesis of malignant ventricular arrhythmias responsible for SCD and the presence of coronary artery disease (CAD) is an aggravating factor. LÄS MER

  3. 22. 12-14 week scan with emphasis on risk assessment for fetal structural malformations and fetal loss

    Författare :Maria-Dorothea Westin; gynekologisk och prenatal ultraljudsdiagnostik Obstetrisk; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Obstetrik; gynekologi; andrologi; reproduktion; sexualitet; reproduction; sexuality; Obstetrics; gynaecology; andrology; Miscarriage; Malformation; Congenital cardiac defect; Nuchal translucency; Prenatal diagnosis; Medicin människa och djur ; Medicine human and vertebrates ; Risk assessment;

    Sammanfattning : The aim was to evaluate first trimester nuchal translucency (NT) measurement for detection and risk assessment of fetal malformations and fetal loss. 39 572 pregnant women were randomised to either a routine ultrasound scan at 12-14 weeks including NT measurement or to a routine scan at 18-20 weeks. LÄS MER

  4. 23. Diagnosis of interatrial shunts and the influence of patent foramen ovale on oxygen desaturation in obstructive sleep apnea

    Författare :Magnus C Johansson; Göteborgs universitet; []
    Nyckelord :Patent foramen ovale; atrial septal defect; obstructive sleep apnea; contrast transesophageal echocardiography; percutaneous closure;

    Sammanfattning : Patent foramen ovale (PFO) is found in 27% of the population and although mostly asymptomatic, PFO has been associated with e.g. cryptogenic stroke and, rarely, also with oxygen desaturation. PFO and atrial septal defects may nowadays be closed percutaneously without open heart surgery. LÄS MER

  5. 24. Physiological changes in mice deficient in different subtypes of thyroid hormone receptors : a focus on studies of heart and muscle

    Författare :Catarina Johansson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :heart rate; ECG; body temperature; [beta]-adrenergic receptor density; thyroid hormone; isometric twitch; SERCa;

    Sammanfattning : The aim of these studies was to determing the specific roles of the different subtypes of thyroid hormone receptors (TR), with focus on heart and muscle function, by using mice deficient in TR[alpha]1, TR[beta] (both TR[beta]1 and TR[beta]2 subtypes) and TR[alpha]1/[beta]. For this purpose, new techniques were set up to study various physiological parameters in these mice. LÄS MER

  7. 25. Darier disease : more than skin deep

    Författare :Philip Curman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Darier disease (DD) is a severe, inherited dermatological disorder with a characteristic clinical and histopathological appearance. It is caused by mutations in the ATP2A2 gene, encoding a Ca2+ pump in the endoplasmic reticulum, Sarco/Endoplasmic Reticulum Ca2+-ATPase 2 (SERCA2), which has been found to be an essential regulator of cellular Ca2+ homeostasis. LÄS MER