Sökning: "hazard ratio"

Visar resultat 1 - 5 av 192 avhandlingar innehållade orden hazard ratio.

  1. 1. Associations of type 2 diabetes mellitus with cancer and autoimmune diseases. A population-based epidemiological study in Sweden

    Författare :Xiangdong Liu; Allmänmedicin och klinisk epidemiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Type 2 diabetes mellitus; cancer; autoimmune disease; cause of death; hazard ratio; standardized incidence ratio; survival; risk factor;

    Sammanfattning : This thesis aimed to search for epidemiological evidence supporting the associations of type 2 diabetes mellitus (T2DM) with cancer and autoimmune diseases (ADs) by analysing several Swedish national registries. T2DM shares risk factors with cancer, such as obesity, diet, stress, and physical inactivity. LÄS MER

  2. 2. Interleukin 6 trans-signalling : cardiovascular risk marker or therapeutical target?

    Författare :Louise Ziegler; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Background: Interleukin (IL) 6 signals in two pathways. In classical signalling, essential in antimicrobial defence and tissue regeneration, IL6 binds the membrane- bound IL6 receptor (IL6R) which associates with the signal transducing receptor gp130. LÄS MER

  3. 3. Essays on the Assumption of Proportional Hazards in Cox Regression

    Författare :Inger Persson; Kenneth Carling; Uppsala universitet; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; Informatics; computer and systems science; Proportional hazards; Cox regression; Proportionality assumption; Informatik; data- och systemvetenskap; Informatics; computer and systems science; Informatik; data- och systemvetenskap; statistik; Statistics;

    Sammanfattning : This thesis consists of four papers about the assumption of proportional hazards for the Cox model in survival analysis. The first paper compares the hazard ratio estimated from the Cox model to an exact calculation of the geometric average of the hazard ratio when the underlying assumption of proportional hazards is false, i.e. LÄS MER

  4. 4. Renal insufficiency, mortality and myocardial infarction

    Författare :Martin Holzmann; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP;

    Sammanfattning : Background: Patients with dialysis-dependent renal insufficiency (RI) have a markedly increased risk of dying or developing cardiovascular disease. Among patients who have coronary heart disease (CHD), moderate or severe RI is associated with increased mortality. LÄS MER

  5. 5. Biomarker mRNAs for staging and prognosis of colorectal cancer

    Författare :Lina Ohlsson; Marie-Louise Hammarström; John Shively; Umeå universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; immunologi; Immunology;

    Sammanfattning : Mesenteric lymph node (ln) metastasis is the single most important prognostic characteristic in colorectal cancer (CRC). The ln status is used for staging and is a decisive selection criterion for postoperative adjuvant therapy. However, it is difficult to accurately determine ln status by routine histopathology (H&E). LÄS MER