Sökning: "harbor structures"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden harbor structures.

  1. 1. Service Life Assessment of Harbor Structures - Case studies of chloride ingress into concrete and sheet piling corrosion rates

    Författare :Henrik Wall; Avdelningen för Byggnadsmaterial; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; chloride ingress; sampling methods; corrosion rates; sheet piling; ultra-sonic measurements; service life; durability; quay structures; harbor structures;

    Sammanfattning : The two most used building materials in harbor structures are undoubtedly steel and concrete. These two materials are often combined in the structures of wharfs and quays where the steel sheet pile walls often have cap beams of reinforced concrete. LÄS MER

  2. 2. Dynamics of higher order chromatin structures

    Författare :Xingqi Chen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : During the last few decades, the intensive focus on microscopy observations and genome sequencing analyses has proved that the genomic DNA is packaged in the non-random manner in the nucleus of interphase cells. Accumulated evidence have thus documented that the chromatin organization in 3D plays key roles in central biological processes, such as transcription, replication and DNA repair. LÄS MER

  3. 3. Prediction, Design and Determination of Protein Structures

    Författare :Sebastian Rämisch; Biokemi och Strukturbiologi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; protein design; Rosetta; Fold-and-Dock; leucine rich repeat proteins; coiled-coils; molecular replacement; ab initio phasing; temperature stability; fluorescent proteins;

    Sammanfattning : The three-dimensional structure of protein is encoded in its amino acid sequence. Modern structure prediction algorithms make it possible to predict the structure of small proteins using sequence information alone. LÄS MER

  4. 4. Synthesis of Bioactive Analogues of Marasmane Dialdehydes

    Författare :Daniel Röme; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organisk kemi; Organic chemistry; Cancer; Enantioselective synthesis; Totalsynthesis; Semisynthesis; Cytotoxicity; Anti-tumor activity; Isovelleraloids; Marasmic acid; Marasmane dialdehydes; Isovelleral;

    Sammanfattning : The modification of drugs into pro-drugs is an attractive concept allowing you to tweak the chemical and physical properties of a drug without changing the original structure of the active compound. In principle, any compound possessing a preferred biological activity can be transformed into a pro-drug. LÄS MER

  5. 5. Engineering protein-carbohydrate interactions - lessons from natural and evolved carbohydrate binding modules

    Författare :Laura von Schantz; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; carbohydrate binding modules protein engineering affinity affinity maturation phage display specificity crystallography cellulose derivatives;

    Sammanfattning : Protein-carbohydrate interactions are of central role in all living organism. In the studies presented in this thesis several strategies for engineering such interactions have been investigated. In the first study the binding affinity of a carbohydrate binding module (CBM) was improved a 100-fold through affinity maturation. LÄS MER