Sökning: "half-lives"

Visar resultat 41 - 45 av 55 avhandlingar innehållade ordet half-lives.

  1. 41. Polybrominated diphenyl ethers and Tetrabromobisphenol A : Chemical synthesis, X-ray crystallography and Photochemical degradation

    Författare :Johan Eriksson; Åke Bergman; Lars Eriksson; Mats Tysklind; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Environmental chemistry; Miljökemi;

    Sammanfattning : In the 1960s’ several manmade chemicals were detected in the environment, far from their sources. The most well known, and most likely those with the largest impact on the society, were DDT and its related compounds, and PCBs. These anthropogenic compounds were characterised as persistent organic pollutants (POPs). LÄS MER

  3. 42. Pharmacokinetics and pharmacodynamics of aminoglycosides

    Författare :Barbro Isacsson; Stig Holm; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The pharmacokinetics of amikacin in humans and the pharmacodynamic effects, i.e. initial killing and postantibiotic effect (P AE), of the aminoglycosides were studied in this thesis. LÄS MER

  4. 43. Rigidity of the Doubly-Magic 100Sn Core

    Författare :Matej Lipoglavsek; Partikel- och kärnfysik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; in-beam gamma-ray spectrscopy; nuclear structure; fusion-evaporation reactions; nuclear shell model; quadrupole polarization charge; doubly-magic nucleus; Nuclear physics; Kärnfysik; Fysicumarkivet A:1998:Lipoglavšek;

    Sammanfattning : The doubly magic nucleus 100Sn represents a crucial test for the nuclear shell model, which is a widely used model for a quantitative description of nuclei. Excited states in 100Sn are experimentally not accessible with present day techniques, but it is possible to gain insight into its structure by studying the properties of excited states of neighboring nuclei. LÄS MER

  5. 44. Peptide nucleic acid conjugates as artificial ribonucleases : Cu2+ and Zn2+-dependent PNAzymes

    Författare :Olivia Luige; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Synthetic modified oligonucleotides are gaining momentum as powerful therapeutic tools used in the treatment of life-threatening diseases. Degradation of disease-related RNA sequences is one of the goals achieved with oligonucleotide therapeutics, albeit the currently available technologies rely on the recruitment of endogenous enzymes, RNase H or RISC, limiting the chemical architecture of oligonucleotide drugs. LÄS MER

  7. 45. Studies of myc gene expression and a novel endoribonuclease activity

    Författare :Anders Wennborg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :c-myc; B-myc; heat-shock; mRNA degradation; endoribonucleases; AUUUAmotifs; RNase E.;

    Sammanfattning : The general aim of this work was to study the regulation of cellular oncogene expression, with emphasis on the c-myc gene, which is de-regulated in several human and animal tumors. The steady-state expression level of c-myc mRNA or protein was analyzed in panels of human Blymphoid cell lines with different growth and transformation properties, and the general observation was a co-variation between high c-myc expression and a more malignant phenotype of the cell lines. LÄS MER