Sökning: "haematopoietic cells"

Visar resultat 1 - 5 av 36 avhandlingar innehållade orden haematopoietic cells.

  1. 1. Mechanisms for Targeting of Proteins to Secretory Lysosomes of Haematopoietic Cells

    Författare :Hanna Rosén; Avdelningen för hematologi och transfusionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellulära vätskor; Haematology; extracellular fluids; haematopoietic cells; Medicin människa och djur ; Medicine human and vertebrates ; secretory lysosomes; protein targeting;

    Sammanfattning : The cells of the innate immune system are essential for the host's first line defence against infection. Among these cells the neutrophil granulocyte has a central role by the production of antibiotic proteins and peptides. LÄS MER

  3. 2. Haematopoietic Serine Proteases : A Cleavage Specificity Analysis

    Författare :Michael Thorpe; Lars Hellman; Urban Gullberg; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mast cell; cleavage specificity; phage display; chymase; serine protease; granzyme; fish protease;

    Sammanfattning : Mast cells are innate immune cells, historically involved in allergy responses involving IgE. Through this, they have earned a reputation as a fairly detrimental cell type. Their beneficial roles remain somewhat enigmatic although they clearly have the ability to modulate the immune system. LÄS MER

  4. 3. MESENCHYMAL STEM- AND STROMAL CELLS IN BONE MARROW AND OSTEOSARCOMA

    Författare :Jan Claas Brune; Stamcellscentrum (SCC); []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mesenchymal stem cells; stromal cells; bone marrow stem cells; tumour stroma; stroma-directed anti-tumour therapy; osteosarcoma;

    Sammanfattning : Primary mesenchymal stem cells (MSC) play a central role in bone marrow (BM) and during haematopoiesis. Yet, the exact phenotype and spatial distribution of primary MSC in the human BM are unknown. Their cultured progeny are promising candidates for clinical applications. LÄS MER

  5. 4. Novel Insights into Haematopoietic Stem Cell Regulation and Function

    Författare :Sarah Warsi; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Haematopoiesis; Haematopoietic stem cell; Stem cell regulation; Haematopoietic stem cell transplantation;

    Sammanfattning : The haematopoietic stem cell (HSC) is a somatic stem cell essential for life long haematopoiesis; HSCs have the capability to differentiate into all mature types of blood cells and can also undergo self-renewal to maintain their own numbers. They also have the potential to reconstitute a complete haematopoietic system following HSC transplantation, also known as bone marrow transplantation, which is used to treat many haematopoietic disorders. LÄS MER

  7. 5. Endothelial cells : dysfunction and repair mechanisms

    Författare :Elzafir Elsheikh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Endothelial cells; endothelial progenitor cells; Wegener s granulomatosis; atherosclerosis; myocardial infarction; menstruation cycle; stromal cell-derived factor-1;

    Sammanfattning : Endothelial cells (ECs) are crucial component of the normal vascular wall, providing an interface between the bloodstream and surrounding tissue of the blood vessel wall. Endothelial progenitors cells (EPCs) circulate in the blood and migrate to regions of the circulatory system with injured endothelium and ischemic tissues. LÄS MER