Sökning: "gut microbe models"

Hittade 4 avhandlingar innehållade orden gut microbe models.

  1. 1. Influence of gut microbiota on xenobiotic toxicity in a Caenorhabditis elegans model with a focus on arsenic and PFAS

    Författare :Jagadish Mangu; Jana Jass; Abul Mandal; Nektarios Tavernarakis; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; C. elegans; physiological responses; gut microbe models; arse-nite; arsenate; PFAS; PFOS;

    Sammanfattning : Exposure to environmental toxins presents a hazard to humans. Inorganic metalloid- arsenic (As), organic chemicals- per and poly-fluoroalkyl substances (PFAS) are frequently detected in the environment. Exposure to As and PFAS is associated with multiple adverse effects in humans and animals. LÄS MER

  3. 2. Metabolic Modeling of the Gut Microbiome-Host Interactions and Meta’omics Integration

    Författare :Saeed Shoaie; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; meta’omics; complexity; obesity; network topology; Gut microbiome; genome-scale metabolic model; gene richness; CASINO; systems biology; flux balance analysis; diabetes;

    Sammanfattning : A large number of microbes with different strain types occupy the human gut. These gut inhabitant microbes have key roles in decomposition of indigestible dietary macronutrients before they are metabolised by the host. LÄS MER

  4. 3. In silico analysis of microbial communities through constraint-based metabolic modelling

    Författare :Parizad Babaei; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; fermented food production; metagenomics; genome-scale metabolic model; community modelling; malnourishment; Microbial community; systems biology; lactic acid bacteria; gut microbiota; uniform randomised sampling;

    Sammanfattning : Microbial communities are involved in many vital biological processes from elemental cycles to sustaining human health. The bacterial assemblages are remarkably under-studied as they are reluctant to grow in the laboratory conditions. LÄS MER

  5. 4. Immune variation in infectious disease and during development early in life

    Författare :Lucie Solène Tiaré Rodriguez; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The human immune system is not only a complex system but a highly dynamic and heterogenous one. It consists of many specialized cells that stimulate and inhibit each other via proteins and physical interactions. LÄS MER