Sökning: "growth-inhibition"

Visar resultat 1 - 5 av 92 avhandlingar innehållade ordet growth-inhibition.

  1. 1. Mesenchymal Stem Cells in Tumor Growth Inhibition and Cartilage Differentiation

    Författare :Laura Varas; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper; Medicine human and vertebrates ; Medicin människa och djur ; mesenchymal stem cell; Biomedical sciences; tumor growth inhibition; FGF2; cartilage; integrin alpha11beta1; integrin alpha10beta1;

    Sammanfattning : The work presented in this thesis has been focused on mesenchymal stem cells (MSCs). In the two first studies, the effects of MSCs on tumor growth and development in vitro and in vivo was investigated. LÄS MER

  3. 2. Too close for comfort : The role of Contact-Dependent growth Inhibition (CDI) in interbacterial competition and cooperation

    Författare :Marcus Wäneskog; Sanna Koskiniemi; Paul Rainey; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; bacterial interactions; cell-cell binding; contact-dependent growth inhibition; CDI; CdiB; CdiA; CdiI; outer-membrane receptor; BamA; OmpC; OmpF; extracellular toxin delivery; Toxin-Antitoxin; TA-system; persister cells; stress tolerance; stress response; rpoS; rssB; quorum sensing; multicellular behavior; Biologi med inriktning mot mikrobiologi; Biology with specialization in Microbiology;

    Sammanfattning : Contact-Dependent growth inhibition (CDI) was discovered in 2005 in the E. coli isolate EC93. Since then our knowledge of CDI systems and their impact on bacterial communities have increased exponentially. LÄS MER

  4. 3. Expressions of mercury-selenium interaction in vitro

    Författare :Peter Frisk; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Oncology; growth inhibition; inorganic mercury; interaction; organic mercury; selenite; selenomethionine; toxicity; uptake; Onkologi; Oncology; Onkologi; Biomedical Radiation Science; biomedicinsk strålningsvetenskap;

    Sammanfattning : Interaction between mercury and selenium has previously been observed both in man and in animals. The aim of this work was to study expressions of interaction between mercury and selenium in human K-562 cells. LÄS MER

  5. 4. On the binding of growth-promoting polyamines to proteoglycans: Implications for growth-regulation and polycation-mediated gene transfer

    Författare :Mattias Belting; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; cationic lipid.; gene transfer; gene therapy; cell growth; polyamine transport; spermine; polyamine; growth-inhibition; heparan sulphate; dermatan sulphate; Proteoglycan; glycosaminoglycan; cytogenetics; Genetik; cytogenetik;

    Sammanfattning : Initial investigations were directed at studying the interaction between polyamines and various glycosaminoglycans (GAGs). The polyamine spermine displayed binding to dermatan sulphate (DS) and heparan sulphate (HS) with similar (Kd, 3.9 x 10-4 M) and higher (Kd, 0.37 x 10-6 M) affinity, respectively, than to DNA. LÄS MER

  7. 5. Involvement of Heparan Sulphate Biosynthesis and Turnover in Cell Proliferation. A Novel Role for Nitric Oxide in Recycling of Heparan Sulphate Proteoglycans

    Författare :Katrin Mani; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; nitrite.; nitric oxide; growth-inhibition; xyloside; glypican; heparan sulphate; Proteoglycan; glycosaminoglycan; Clinical biology; Klinisk biologi;

    Sammanfattning : The present investigation focuses on the role of HS metabolism in cell proliferation. The effect of the HS priming ß-D-xyloside, 2-(6-hydroxynaphthyl)-O-ß-D-xylopyranoside (Xyl-2-Nap-6-OH) on the proliferation of normal and transformed cells was studied. LÄS MER