Sökning: "growth plate"

Visar resultat 6 - 10 av 116 avhandlingar innehållade orden growth plate.

  1. 6. Identification of novel growth hormone-regulated factors

    Författare :Björn Andersson; Göteborgs universitet; []
    Nyckelord :Growth hormone; idiopathic short stature; growth hormone deficient; prepubertal; children; genomic; proteomic;

    Sammanfattning : The studies described in this thesis aimed to identify novel factors involved in the regulation of longitudinal growth and bone mineralization in response to growth hormone (GH) treatment. This was done by performing a single factor study (Paper I) where it was found that growth response was negatively correlated with adiponectin levels during the first year of GH treatment in short prepubertal children. LÄS MER

  3. 7. High-load injuries in the adolescent athlete's hip; clinical and experimental studies and outcome measures

    Författare :Pall Jonasson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hip; groin; athlete; adolescent; femoroacetabular impingement; cam; pincer; osteoarthritis; porcine; epiphyseal plate; growth; validity; reliability; iHOT; HAGOS;

    Sammanfattning : The diagnosis and treatment of hip and groin symptoms has often been a problem area in orthopaedics and sports medicine. Hip and groin pain and injuries are common among athletes and in the increasingly active population. LÄS MER

  4. 8. Estrogen actions in the growth plate cartilage

    Författare :Maryam Iravani; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Estrogens may influence bone growth locally or systemically via the estrogen receptors alpha (ERα), beta (ERβ) and G protein-coupled estrogen receptor 1 (GPER-1). In Paper I, our study showed that the treatment of ovariectomized C57BL/6 mice with a selective ERα agonist 1,3,5-tris(4-hydroxyphenyl)-4-propyl-1H-pyrazole (PPT) reduced growth plate height and hypertrophic zone height suggesting that the effect was induced via ERα. LÄS MER

  5. 9. The role of estrogen in growth plate chondrogenesis

    Författare :Ola Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Overall body proportion is determined by the size of the skeleton, which in turn is determined by the rate and duration of longitudinal bone growth. Longitudinal bone growth occurs at the growth plate and is regulated by a variety of hormones and growth factors. LÄS MER

  7. 10. Local regulation of growth plate chondrocytes : molecular mechanisms and implications for longutidinal growth

    Författare :Anenisa de Cohelho Andrade; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The regulation of linear growth is a complex and intriguing process that has the growth plate cartilage as its final target. Growth plate is a specialized cartilage localized in the end of the long bones between the epiphyseal and metaphyseal bone. LÄS MER