Sökning: "growth inhibition"

Visar resultat 21 - 25 av 646 avhandlingar innehållade orden growth inhibition.

  1. 21. Prostate cancer and bone cell interactions : implications for metastatic growth and therapy

    Författare :Annika Nordstrand; Pernilla Wikström; Anders Widmark; Jonas Nilsson; Päivi Östling; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; onkologi; Oncology;

    Sammanfattning : The skeleton is the most common site of prostate cancer bone metastasis, and at present, there are no curable treatments for these patients. To further understand what stimulates tumor cell growth in the bone microenvironment and to find suitable therapies, reliable model systems are needed. LÄS MER

  3. 22. Local regulation of growth plate chondrocytes : molecular mechanisms and implications for longutidinal growth

    Författare :Anenisa de Cohelho Andrade; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The regulation of linear growth is a complex and intriguing process that has the growth plate cartilage as its final target. Growth plate is a specialized cartilage localized in the end of the long bones between the epiphyseal and metaphyseal bone. LÄS MER

  4. 23. The effects of internally expressed Contact-Dependent growth Inhibition (CDI) toxins in bacteria

    Författare :Magnus Stårsta; Sanna Koskiniemi; Pierre Genevaux; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : Bacteria, both pathogenic and non-pathogenic, have developed multiple forms of competition mechanisms to combat each other including, but not limited to, Contact-Dependent growth Inhibition (CDI) systems, Type VI Secretion Systems and the associated Rearrangement hotspot (Rhs) toxin system. These systems usually confers a great fitness advantage as they allow for precise delivery of toxic molecules into competing bacteria whilst sister cells are protected from auto-inhibition by producing a cognate immunity protein. LÄS MER

  5. 24. Physiology of Caldicellulosiruptor saccharolyticus: a hydrogen cell factory

    Författare :Karin Willquist; Teknisk mikrobiologi; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; growth activation; hydrogen tolerance; hydrogen yields CO2 inhibition; physiology; enzyme kinetics; Caldicellulosiruptor saccharolyticus; biohydrogen; energy metabolism;

    Sammanfattning : A high substrate conversion efficiency is a prerequisite for an economically feasible biohydrogen production. Caldicellulosiruptor saccharolyticus is a strictly anaerobic extreme thermophilic bacterium that is able to convert the theoretical maximum of 4 mol/mol glucose to H2. LÄS MER

  7. 25. Effects of growth factors on chondrocyte proliferation and differentiation

    Författare :Caroline Edwall-Arvidsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Growth plate cartilage; limb buds; growth factors; proliferation; differentiation; collagens; c-fos; ALP;

    Sammanfattning : Longitudinal bone growth is regulated at the level of growth plate chondrocytes by circulating or locally produced hormones and growth factors. Present investigation focused on the effects of growth hormone (GH) and growth factors on chondrocyte proliferation and differentiation during pre- and postnatal cartilage development. LÄS MER