Sökning: "growth hormone"
Visar resultat 6 - 10 av 392 avhandlingar innehållade orden growth hormone.
6. Growth hormone responsiveness in children : results from Swedish multicenter clinical trials of growth hormone treatment
Sammanfattning : The general aims of the thesis were to study GH responsiveness by estimation of pharmacokinetics and bioavailability of injected recombinant human GH (rhGH), of growth response as gain in heightSDS during childhood and puberty, and IGF-I response as change in circulating IGF-ISDS and IGFBP3SDS. Methods Short children were recruited during 1988–1999 into two national randomized multicentre clinical trials on growth until adult height. LÄS MER
7. Growth hormone in the brain : Focus on cognitive function
Sammanfattning : Cognitive impairments are an increasing health problem worldwide. In the developed countries, the average life expectancy has dramatically increased over the last decades, and with an elderly population more cases of cognitive impairments appear. LÄS MER
8. Prediction Models and Pharmacogenomics in Adult Growth Hormone Deficiency
Sammanfattning : The overall aim of this thesis was to study clinical and genetic factors that influence response to growth hormone replacement therapy (GHRT) in GH deficient (GHD) adults. The patients were part of a cohort of adults with hypopituitarism and severe GHD who were studied before and after 12 months of GHRT. LÄS MER
9. Growth Hormone and Anabolic Androgenic Steroids : Effects on Neurochemistry and Cognition
Sammanfattning : Growth hormone (GH) stimulates growth and metabolism but also displays profound effects on the central nervous system (CNS). GH affects neurogenesis and neuroprotection, and has been shown to counteract drug-induced apoptosis in the brain. LÄS MER
10. Long-term effects of growth hormone replacement in hypopituitary adults on body composition, bone mass and cardiovascular risk factors
Sammanfattning : Growth hormone (GH) deficient (GHD) adults have decreased bone mass and muscle strength, impaired body composition, disturbed serum lipid pattern and increased morbidity and mortality in cardiovascular and cerebrovascular diseases. GH replacement normalizes most of these aberrations within the first year of treatment. LÄS MER