Sökning: "granulocytic"
Visar resultat 1 - 5 av 18 avhandlingar innehållade ordet granulocytic.
1. Ehrlichia in animals and humans
Sammanfattning : Ehrlichia phagocytophila is a tick-borne pathogen of domestic animals, which has recently been acknowledged also as a human pathogen. It is a strictly intracellular bacterium, infecting granulocytes of the host, sometimes resulting in clinical disease - granulocytic ehrlichiosis - with manifestations ranging from mild flu-like conditions to severe infections with multi-organ failure and death. LÄS MER
2. β2 integrin-induced signal transduction in granulocytic cells
Sammanfattning : Neutrophil granulocytcs are highly mobile, phagocytic white blood cells whose motile functions are critically dependent on adhesion receptors belonging to the B2 integrin subfamily. These integrins are vital for neutrophil functions due to their ability to generate intracellular signals. LÄS MER
3. New aspects on retinoic acid induced HL-60 granulocytic differentiation
Sammanfattning : The underlying mechanisms of myeloid cell differentiation are still not entirely elucidated. It is therefore an urgent task to extent the basis for a comprehensive model of granulocytes differentiation. A primary goal for studies has been the identification of differentiation markers. LÄS MER
4. Cytokine responses in human Lyme borreliosis : The role of T helper 1-like immunity and aspects of gender and co-exposure in relation to disease course
Sammanfattning : Lyme borreliosis was first described some 30 years ago in the USA. Today, it is the most common vector borne disease in Europe and the USA. The disease can have multiple stages and symptoms can manifest from various parts of the body; joints, skin heart and nervous system. In Europe, neuroborreliosis is the most frequent late stage diagnosis. LÄS MER
5. The role of the leukemia-associated ETO homologue repressors in hematopoiesis
Sammanfattning : The fusion protein AML1-ETO is observed in acute myeloid patients with the chromosomal translocation t(8;21). Cells with this chimeric protein have impaired granulocytic and erythroid differentiation with accumulation of myeloblasts. The transcriptional co-repressor ETO (Eight Twenty One) was identified from the cloning of AML1-ETO. LÄS MER