Sökning: "gram negative bacteria"

Visar resultat 36 - 40 av 236 avhandlingar innehållade orden gram negative bacteria.

  1. 36. Deoxyribonucleoside kinases in bacteria, plants and humans

    Författare :Anders Ranegaard Clausen; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; anti-viral drugs; gene therapy; cancer; evolution; nucleoside analog; deoxyribonucleoside kinase; thymidine kinase;

    Sammanfattning : Deoxyribonucleoside triphosphates (dNTPs) are the building blocks of DNA and can be synthesized either de novo or via salvage pathways. The first reaction in the salvage pathway of dNTPs is the conversion of deoxyribonucleosides (dN) into the deoxyribonucleoside monophosphate (dNMP). LÄS MER

  3. 37. On extrinsic and intrinsic organizational themes in gram negative bacteria and their role in evolution and virulence of the bacterial genus Salmonella spp

    Författare :Anders Folkesson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Salmonella; fimbriae; evolution; cell wall; peptidoglycan;

    Sammanfattning : Gram-negative bacteria are composed of intrinsic organizational themes such as outer and inner membrane, cell wall, and replicons. Themes that not only determine the body-plan and physical properties but also set the boundaries for choice of life style and evolution of the organisms. LÄS MER

  4. 38. Virulence mechanisms of two gram negative bacteria : studies on Escherichia coli hemolysin HlyA and on the interaction of Brucella abortus with non-phagocytic cells

    Författare :Caterina Guzman-Verri; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Virulence factors may be classified in two general groups: those that cause damage to the host and those that promote bacterial colonization and invasion. In this study, the tissue damaging Escherichia coli hemolysin HlyA and the mechanism of internalization of the intracellular parasite Brucella abortus were investigated. LÄS MER

  5. 39. Antibiotic resistance in Gram-negative bacilli : with focus on cephalosporin resistance mechanisms in Escherichia coli and Klebsiella pneumoniae

    Författare :Owe Källman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Objectives: The objectives of this thesis were to study mechanisms conferring cefuroxime resistance in clinical non-ESBL (extended-spectrum beta-lactamase) producing isolates of Escherichia coli and Klebsiella pneumoniae, as well as the presence of co-resistance to other antibiotics in the K. pneumoniae isolates. LÄS MER

  7. 40. Interactions between innate immune effectors and multidrug resistant bacteria

    Författare :Harpa Káradóttir; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Antibiotic resistance is an increasingly difficult problem in the clinic, where conventional antibiotics are failing, and new alternative solutions are in high demand. Infections caused by Gram-negative bacteria with multi drug resistance (MDR) mechanisms are increasing globally, and treatment options are limited. LÄS MER