Sökning: "gram negative bacteria"

Visar resultat 31 - 35 av 236 avhandlingar innehållade orden gram negative bacteria.

  1. 31. Molecular basis for trimethoprim and sulphonamide resistance in Gram negative pathogens

    Författare :Malin Grape; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Resistance to antibiotics is becoming an important global public health problem. Infectious diseases are still among the major causes of disease and death in many parts of the world and the possibilities to treat bacterial infections are now threatened due to the spread of antibiotic resistance. LÄS MER

  3. 32. Assembly and adhesive properties of curli : a stationary phase-specific surface organelle in Gram-negative enteric bacteria

    Författare :Mårten Hammar; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Escherichia colilcurli fimbriae csgstarvation;

    Sammanfattning : The natural environments of bacteria are most often characterized by suboptimal conditions for growth, e. g., limited supply of nutrients. Consequently, periods of dormancy or negligible growth are the rule rather than the exception. LÄS MER

  4. 33. Statistical molecular design, QSAR modeling, and scaffold hopping – Development of type III secretion inhibitors in Gram negative bacteria

    Författare :Markus Dahlgren; Mikael Elofsson; Bo Nordén; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Statistical molecular design; QSAR; synthesis; type III secretion; virulence; scaffold hopping; Bioorganic chemistry; Bioorganisk kemi; datorlingvistik; computational linguistics;

    Sammanfattning : Type III secretion is a virulence system utilized by several clinically important Gram-negative pathogens. Computational methods have been used to develop two classes of type III secretion inhibitors, the salicylidene acylhydrazides and the acetylated salicylanilides. LÄS MER

  5. 34. Studies on mRNA turnover in bacteria

    Författare :Martin Persson; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Microbiology; aprE; GlpP; glpD; mRNA secondary structure; Bacillus subtilis; mRNA stability; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Genetic information, which is stored in DNA, is transferred to messenger RNA (mRNA) in a process called transcription. mRNAs are then translated by ribosomes into proteins which, with some important exceptions, catalyze chemical reactions in cells. Since cells must be able to adapt to changes in the environment, mRNAs must be unstable. LÄS MER

  7. 35. Innate and acquired immunity to commensal bacteria

    Författare :Christina Hessle; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The innate immune system recognises molecular patterns shared by large groups of micro-organisms. Monocytes and macrophages respond to microbes by production of substances which act in concert to promote effective clearance of bacteria. LÄS MER