Sökning: "gonzalez de valdivia"

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  1. 1. Studies on translation initiation and gene expression in Escherichia coli

    Författare :Ernesto I. Gonzalez de Valdivia; Leif Isaksson; Stephen Douthwaite; Stockholms universitet; []
    Nyckelord :Downstream region; NGG codons; abortive translation; drop-off; Shine-Dalgarno sequence; gene expression and Escherichia coli; NATURAL SCIENCES; NATURVETENSKAP;

    Sammanfattning : In prokaryotes, several mRNA sequences surrounding the initiation codon have been found to influence the translation process; these include the downstream region and its codon context, the Shine-Dalgarno sequence and the S1 ribosomal protein-binding site. In this thesis, the purpose has been to study the role of the downstream region and Shine-Dalgarno-like sequences on early translation elongation and gene expression in Escherichia coli. LÄS MER