Sökning: "glycosides"

Visar resultat 21 - 25 av 52 avhandlingar innehållade ordet glycosides.

1. 21. Synthesis of complex carbohydrates corresponding to the Lewis b blood group antigen and Vibrio cholerae polysaccharide structures

   Författare :Dominika Turek; Ulf Nilsson; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic Chemistry; organisk kemi;

   Sammanfattning : This thesis is divided into two parts. The first part describes the syntheses of the Lewis b blood group antigen hexasaccharide and parts thereof. The Leb blood group antigen is one of the binding epitopes for the Helicobacter pylori bacteria in the human stomach. LÄS MER

3. 22. Exploring beta-mannan acting glycosidase families in hydrolysis and mannosyl transfer

   Författare :Simon Birgersson; Biokemi och Strukturbiologi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; glycoside hydrolases; beta-mannanase; Transglycosylation; enzymatic synthesis; Enzyme synergy; enzyme engineering; MALDI-TOF; HPLC; NMR;

   Sammanfattning : The thesis revolves around the study of glycoside hydrolases (GH), specifically GH5 β-mannanases and GH36 α-galactosidase (I-III), as well as a GH130 mannoside phosphorylase (I, IV). These enzymes are investigated for their actions on and conversion of hemicellulosic β-mannan, including food-grade galactomannan and softwood galactoglucomannan, along with manno-oligosaccharides (MOS) derived from such polymers. LÄS MER

4. 23. Structural studies of two bacterial polysaccharide antigens : synthesis and chemical modification of low molecular weight carbohydrates

   Författare :Carmen Ortega; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : The structures of two bacterial antigens, one a capsular polysaccharide from Klebsiella K66 and the other a lipopolysaccharide from Escherichia coli 0:6, have been determined, using specific degradations and spectrochemical studies. Two glycosidation methods are described. LÄS MER

5. 24. Carbohydrate-Based Inhibitors of Pathogen Adhesion to Cell Surface Glycoconjugates

   Författare :Henrik C Hansen; Centrum för analys och syntes; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Galabiose analogs; Globotriose analogs; Escherichia coli; verotoxin; PapG adhesion; Streptococcus suis; Dendrimers; Multivalency; Amino-deoxy analogs; Organic chemistry; Inhibitor; Ceramide analogs; Glycoconjugates; Organisk kemi;

   Sammanfattning : The fact that a growing number of pathogens develop resistance against traditional treatment is a growing medical problem. Infections, which until now have been harmless, might turn into life threatening diseases. These problems have led to an intensified search for alternative treatments. Analogs of cell surface glycoconjugates are an alternative. LÄS MER

7. 25. Chemistry of Carbon Nanostructures : Functionalization of Carbon Nanotubes and Synthesis of Organometallic Fullerene Derivatives

   Författare :Claes-Henrik Andersson; Helena Grennberg; Nazario Martín León; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Carbon nanotubes; Fullerenes; Purification; Functionalization; Organometallic complexes; Kemi med inriktning mot organisk kemi; Chemistry with specialization in Organic Chemistry;

   Sammanfattning : This thesis is based on two main parts. The first part concerns purification and functionalization of carbon nanotubes (papers I-III), and the second part is related to the synthesis of organometallic fullerene derivatives (papers IV-VII): Two oxidative methods involving aqueous nitric acid were compared with respect to their capability to introduce carboxylic groups into single walled carbon nanotubes, and several literature methods for esterification and amidation of these groups have been evaluated with focus on efficiency and reproducibility in forming covalently functionalized products soluble in organic media. LÄS MER