Sökning: "glycosaminoglycan"
Visar resultat 21 - 25 av 85 avhandlingar innehållade ordet glycosaminoglycan.
21. Tools for understanding the glycosaminoglycan biosynthesis
Sammanfattning : For cells to function correctly within an organism, they need different systems to communicate with each other. One crucial part of cell signaling is the proteoglycans (PGs) and glycosaminoglycans (GAGs), which are macromolecules that bind different signaling molecules and proteins necessary for processes such as growth and proliferation. LÄS MER
22. Glycosaminoglycan Biosynthesis and Function in Zebrafish Development : Sugars Shaping Skeletons
Sammanfattning : Heparan sulfate (HS) and chondroitin/dermatan sulfate (CS/DS) proteoglycans are glycosylated proteins with important roles in animal development and homeostasis. HS and CS/DS are long, linear glycosaminoglycan (GAG) polysaccharides and attached to a core protein they form proteoglycans. LÄS MER
23. Designing biosensor platforms to study glycosaminoglycan interactions
Sammanfattning : The importance of glycosaminoglycans (GAGs) has been highlighted in many areas of research during recent years. Not only are they important in providing structure and support to our tissues but they also function as interaction partners in the extracellular matrix and at the cell membrane. LÄS MER
24. Syndecan - Regulation and Function of its Glycosaminoglycan Chains
Sammanfattning : The cell surface is an active area where extracellular molecules meet their receptors and affect the cellular fate by inducing for example cell proliferation and adhesion. Syndecans and integrins are two transmembrane molecules that have been suggested to fine-tune these activities, possibly in cooperation. Syndecans are proteoglycans, i.e. LÄS MER
25. Novel chemical and enzymatic routes to the generation of heparin- related polysaccarides
Sammanfattning : Heparin and heparan sulphate (HS) are structurally related polysaccharides influencing various biological processes. The biological functions of heparin/HS largely depend on interactions between the negatively charged polysaccharide chains and a variety of proteins. LÄS MER