Sökning: "glutamine metabolism"

Visar resultat 1 - 5 av 41 avhandlingar innehållade orden glutamine metabolism.

  1. 1. Astrocyte metabolism following focal cerebral ischemia

    Författare :Anna E Thoren; Göteborgs universitet; []
    Nyckelord :Astrocyte; metabolism; focal cerebral ischemia; reperfusion; infarct; [1-14C]acetate; [U-14C]glucose; glutamine; glutamate; ATP; ADP; lactate; MCT4; immunogold cytochemistry;

    Sammanfattning : Stroke is one of the leading causes of disability and death. Most often, stroke results from blockage of an artery in the brain leading to tissue infarction within the perfusion territory of the affected vessel. LÄS MER

  3. 2. Glutamate Turnover and Energy Metabolism in Brain Injury : Clinical and Experimental Studies

    Författare :Carolina Samuelsson; Elisabeth Ronne-Engström; Lars Hillered; Eva Kumlien; Carl-Henrik Nordström; Uppsala universitet; []
    Nyckelord :Neurosciences; glutamate; glutamine; lactate; pyruvate; microdialysis; GLT-1; energy metabolism; intracranial pressure; cerebral perfusion pressure; subarachnoid hemorrhage; ischemia; epilepsy; Neurovetenskap;

    Sammanfattning : During brain activity neurons release the major excitatory transmitter glutamate, which is taken up by astrocytes and converted to glutamine. Glutamine returns to neurons for re-conversion to glutamate. This glutamate-glutamine cycle is energy demanding. LÄS MER

  4. 3. Utilization of single-cell RNA-Seq and genome-scale modeling for investigating cancer metabolism

    Författare :Johan Gustafsson; Chalmers tekniska högskola; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; genome-scale metabolic modeling; cancer; metabolism; single-cell RNA-Seq;

    Sammanfattning : Cancer remains a leading cause of death worldwide, and its dysregulated metabolism is a promising target for therapy. However, metabolism is complex to study – the metabolism of a cell involves the interplay of thousands of chemical reactions that are combined in different ways across tissues and cell types. LÄS MER

  5. 4. Nitrogen and Redox Metabolism in Saccharomyces cerevisiae

    Författare :Eva Albers; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Saccharomyces cerevisiae; glutamate; protein expression; anaerobic physiology; nitrogen metabolism; redox; serine;

    Sammanfattning : Anaerobic conversion of glucose to ethanol by the yeast Saccharomyces cerevisiae has been studied. Glycerol is formed as a by-product in order to maintain the overall redox balance. LÄS MER

  7. 5. PII proteins as global regulators of bacterial nitrogen metabolism

    Författare :Pedro Filipe Teixeira; Stefan Nordlund; Ray Dixon; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Rhodospirillum rubrum; nitrogen metabolism; signal transduction; PII proteins; Biochemistry; Biokemi; Biochemistry; biokemi;

    Sammanfattning : Nitrogen is an essential element to sustain life, being a component of most biological macromolecules. In spite of the abundance of gaseous N2, the availability of nitrogen compounds that can be readily used by most microorganisms is scarce and its production energetically demanding. LÄS MER