Sökning: "glutamate transport"

Visar resultat 6 - 10 av 24 avhandlingar innehållade orden glutamate transport.

  1. 6. Erythrocyte amino acids in health and renal failure and their association to the IGF-I/IGFBP-1 axis

    Författare :José Carolino Divino Filho; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :amino acid; ASP DNA; catabolism dialysis; erythrocytes; glutamate; glutamine; health; human; IGF-I; IGFBP-1; muscle; plasmaprotein intake; rat; renal failure; uraemia;

    Sammanfattning : Abnormalities in amino acids (AA) metabolism in uraemia have mainly been reported to occur in plasma and muscle. No investigation has been undertaken to evaluate the AA levels in plasma, muscle and red blood cells (RBC) simultaneously, although the RBC pool of free AA constitutes a large proportion of the free AA in blood, and RBC are involved in the interorgan transport of AA. LÄS MER

  3. 7. Factors affecting alcohol self-administration : learning, environmental and genetic influences on behaviour

    Författare :Christopher Pickering; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :ethanol; operant self-administration; addiction; reward; learning; lever press response; context; environmental cue; novelty; stress; glutamate; GABA; noradrenaline; PCR; gene expression; functional genomics; prefrontal cortex; hippocampus; amygdala;

    Sammanfattning : Alcoholism is a serious problem for society and is a very difficult disease to treat clinically. Often, the addict has periods of abstinence from alcohol followed by relapse to drinking and this cycle of use/non-use can repeat over many years. LÄS MER

  4. 8. A special role of Na,K-ATPaseand its molecular partners for astrocyte function

    Författare :Nina Illarionova; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Astrocytes are glial cells that express several specific transporters and channels with specialized functions to maintain water, ion and neurotransmitter concentrations in order to preserve normal neuronal function. Astrocytes express two catalytic isoforms of plasma membrane enzyme Sodium Potassium-ATPase (Na,K-ATPase), that are essential for several of astrocyte’s functions. LÄS MER

  5. 9. Studies on aquaporin 4 : a molecular determinant of brain water homeostasis

    Författare :Eli Gunnarson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : A well controlled brain water homeostasis is of utmost importance for an appropriate control of neuronal activity. Astrocytes express the water channel aqauporin 4 (AQP4) and play a key role for the maintenance of brain water homeostasis. Brain edema is a result of perturbed water homeostasis and involves astrocyte swelling. LÄS MER

  7. 10. Studies on astrocyte function : potential roles in brain water homeostasis and neuroprotection

    Författare :Yutong Song; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Astrocytes are essential in brain homeostasis and function, including maintenance of water and ion balance. Astrocytes express the water channel aquaporin 4 (AQP4), implicated in both physiological functions and injury processes associated with brain edema, a common consequence of brain diseases. LÄS MER