Sökning: "glutamate transport"

Visar resultat 1 - 5 av 20 avhandlingar innehållade orden glutamate transport.

  1. 1. Microglial Glutamate Transporters - Regulation of Expression and Possible Physiological Functions

    Författare :Mikael Persson; Göteborgs universitet.; Gothenburg University.; [2007]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; anaphylatoxin; central nervous system; herpes simplex virus; glutamate transport; glutathione; GLT-1; lipopolysaccharide; microglia; neuroinflammation; oxidative stress; protection; tumour necrosis factor-alpha;

    Sammanfattning : Microglia are considered as the immunocompetent cells of the central nervous system (CNS). Being the first line of defence, they have prominent roles in monitoring the homeostasis and the extracellular milieu and can rapidly and specifically react to any disturbances such as brain trauma, ischemia, neurodegenerative diseases, or infections. LÄS MER

  2. 2. Across Borders A Histological and Physiological Study of the Subthalamic Nucleus in Reward and Movement

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Nadine Schweizer; Uppsala universitet.; [2016]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; subthalamic nucleus; STN; basal ganglia; locomotion; hyperlocomotion; rearing; ventral tegmental area; VTA; dopamine; glutamate; vesicular glutamate transporter 2; Vglut2; Parkinson s disease; deep brain stimulation; subpopulation; conditional knock-out; optogenetic; co-expression; in situ hybridization; self-administration; reward behavior; mouse genetics;

    Sammanfattning : The basal ganglia are the key circuitry controlling movement and reward behavior. Both locomotion and reward-related behavior are also modified by dopaminergic input from the substantia nigra and the ventral tegmental area (VTA). LÄS MER

  3. 3. Glutathione in the brain. Studies on efflux and possible implications in neurotoxicity

    Detta är en avhandling från Göteborg

    Författare :Camilla Wallin; Göteborgs universitet.; Gothenburg University.; [2000]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glutathione; excitotoxicity; hypoxia-ischemia; brain; rat; anoxia-aglycemia; g-glutamyl transpeptidase; glutamate; NMDA; oxidative stress; mitochondria; amino acids;

    Sammanfattning : Neuronal cell death in acute insults such as stroke, trauma and epilepsy involves overactivation of glutamate receptors, calcium influx and increased formation of potentially toxic reactive oxygen species. Glutathione is a key component in the antioxidant defense system against reactive oxygen species. LÄS MER

  4. 4. Water transport regulation: Biochemical and structural analyses of eukaryotic aquaporins

    Detta är en avhandling från Göteborg

    Författare :Anna Maria Nyblom; [2008]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; X-ray crystallography; regulation; aquaporins; function; structure; membrane proteins;

    Sammanfattning : Water is essential for all living beings. Aquaporins are water channel proteins embedded in the membranes of cells. These macromolecules are found in all kingdoms of life and they control water homeostasis by diverse regulation mechanisms. LÄS MER

  5. 5. Erythrocyte amino acids in health and renal failure and their association to the IGF-I/IGFBP-1 axis

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Clinical Sciences

    Författare :José Carolino Divino Filho; Karolinska Institutet.; Karolinska Institutet.; [1998]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; amino acid; ASP DNA; catabolism dialysis; erythrocytes; glutamate; glutamine; health; human; IGF-I; IGFBP-1; muscle; plasmaprotein intake; rat; renal failure; uraemia;

    Sammanfattning : Abnormalities in amino acids (AA) metabolism in uraemia have mainly been reported to occur in plasma and muscle. No investigation has been undertaken to evaluate the AA levels in plasma, muscle and red blood cells (RBC) simultaneously, although the RBC pool of free AA constitutes a large proportion of the free AA in blood, and RBC are involved in the interorgan transport of AA. LÄS MER