Sökning: "glucocorticoids"

Visar resultat 16 - 20 av 160 avhandlingar innehållade ordet glucocorticoids.

  1. 16. Life, death ant the role of IGF-I in human multiple myeloma

    Författare :Patrik Georgii-Hemming; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Multiple Myeloma; IGF-I; apoptosis; Fas; glucocorticoids; somatostatin; Genetik; Clinical genetics; Klinisk genetik; Pathology; patologi;

    Sammanfattning : Multiple myeloma (MM) is a clonal expansion of malignant cells with a plasmablast- plasma cell morphology in the bone marrow. It is a fatal disease with a median survival of 2-3 years after start of conventional therapy. LÄS MER

  3. 17. Lung mechanics and airway inflammation in murine models of asthma

    Författare :Sofia Jonasson; Josephine Hjoberg; Hedenstierna Göran; Carl Persson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; allergic asthma; airway inflammation; murine models; lung mechanics; forced oscillation technique; airway reactivity; deep inhalations; oxidative stress; nitric oxide; glucocorticoids.; Clinical physiology; Klinisk fysiologi; klinisk fysiologi; Clinical Physiology;

    Sammanfattning : Allergic asthma is an inflammatory disease of the airways and is characterized by eosinophilic inflammation and increased airway reactivity. In the studies presented in this thesis, lung mechanics and measurements of airway reactivity were assessed in anaesthetized tracheostomized mice by using an animal ventilator (flexiVent®). LÄS MER

  4. 18. Answers of big biological data to unsolved diabetes questions - Unveiling causes of impaired β-cell insulin secretion

    Författare :Alexandros Karagiannopoulos; Diabetes - öcellsexocytos; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glucocorticoids; beta cell; miRNA; type 2 diabetes; insulin secretion; bioinformatics;

    Sammanfattning : .... LÄS MER

  5. 19. Glucocorticosteroid effects on cytokine production: studies in a glucocorticosteroid resistance model and in allergic airway disease

    Författare :Susanne Larsson; allergologi och palliativ medicin Lungmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; GM-CSF; cytokine; glucocorticoids; budesonide; IL-2; IL-4; IL-12; asthma; allergic rhinitis; allergic airway inflammation; Respiratory system; Andningsorganen;

    Sammanfattning : Glucocorticosteroids (GCS) are potent anti-inflammatory drugs, probably due to inhibitory effects on cytokine production. However, a small number of asthma patients seem GCS-resistant. Pro-inflammatory cytokines, such as interleukin-2(IL-2) and IL-4, produced during allergic airway inflammation have been proposed to induce the resistance to GCS. LÄS MER

  7. 20. Induced Growth and Precocious Maturation of the Digestive System in Suckling Rats and Pigs after Exposure to Red Kidney Bean Lectin

    Författare :Ann Linderoth; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; neuropsykologi; neurofysiologi; Neurologi; neurophysiology; neuropsychology; Neurology; Fysiologi; Physiology; Djurfysiologi; Animal physiology; sucrase; lactase; amylase; trypsin; weaning; small intestine; glucocorticoids; endocytosis; dissacchridases; intestinal permeability; PHA; pancreas; Development; phytohaemagglutinin;

    Sammanfattning : The timing of the postnatal development of the gastrointestinal (GI) tract in mammals is influenced by dietary and hormonal factors. It was hypothesized that accelerated GI cell turnover during maturation would result in a precoucios conversion to more mature digestive functions. LÄS MER