Sökning: "glucocorticoids"
Visar resultat 11 - 15 av 160 avhandlingar innehållade ordet glucocorticoids.
11. Systems Biology Based Approaches to Identify Biomarkers in Seasonal Allergic Rhinitis
Sammanfattning : Glucocorticoids (GC) are the most effective anti-inflammatory treatment for seasonal allergic rhinitis (SAR). However, a few patients with SAR show poor response to GC treatment. Hence, there is a clinical need to find biomarkers to predict and monitor treatment response. LÄS MER
12. Role of nuclear receptors in the regulation of human adipose tissue metabolism
Sammanfattning : Nuclear receptors modulate expression of genes involved in adipose tissue (AT) metabolism. Their improved understanding may provide new treatment options for metabolic disorders such as obesity, insulin resistance (IR) and type 2 diabetes (T2D). LÄS MER
13. Effects of immunosuppressive drugs on human adipose tissue metabolism
Sammanfattning : The immunosuppressive agents (IAs) rapamycin, cyclosporin A and tacrolimus, as well as glucocorticoids are used to prevent rejection of transplanted organs and to treat autoimmune disorders. Despite their desired action on the immune system, these agents have serious long-term metabolic side-effects, including dyslipidemia and new onset diabetes mellitus after transplantation. LÄS MER
14. 5-HT2A : a serotonin receptor with a possible role in joint diseases
Sammanfattning : BackgroundSerotonin (5-HT), an amino acid derivative and neurotransmitter, has for long been studied in relation to inflammation. It is an endogenous ligand for several different types of serotonin receptors. The serotonin receptor 5-HT2A has been reported to have a role in the pathophysiology of arthritis in animal experiment models. LÄS MER
15. Addison's disease and type 1 diabetes mellitus
Sammanfattning : .... LÄS MER