Sökning: "gliosis"

Visar resultat 21 - 25 av 42 avhandlingar innehållade ordet gliosis.

  1. 21. Autosomal Dominant Leukodystrophy with Autonomic Symptoms and Rippling Muscle Disease : Translational Studies of Two Neurogenetic Diseases

    Författare :Jimmy Sundblom; Anja Smits; Raili Raininko; Niklas Dahl; Klas Kullander; Åsa Fex-Svenningsen; Marianne de Visser; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Inborn genetic diseases; Leukoencephalopathies; Lamin type B; Muscular disease; Caveolin 3; Neurology; Neurologi;

    Sammanfattning : There is a large variety of diseases caused by single-gene mutations. Although most of these conditions are rare, together they impose a significant burden to the population. LÄS MER

  3. 22. The importance of astroglial cells in ischemia, regeneration and angiogenesis

    Författare :Andrea Lundkvist; Göteborgs universitet; []
    Nyckelord :astrocytes; Müller cells; retina; intermediate filaments; GFAP; vimentin; angiogenesis; VEGF-A; guidance; matrix-metalloprotease;

    Sammanfattning : Astrocytes in the CNS communicate with both neurons and blood vessels. In many CNS pathologies, astrocytes respond by becoming reactive. Whether their performance at this stage is beneficial or detrimental for CNS function is unclear. LÄS MER

  4. 23. Of mice and men : SOD1 associated human amyotrophic lateral sclerosis and transgenic mouse models

    Författare :Karin Sixtensdotter Graffmo; Thomas Brännström; Stefan Marklund; Elisabeth Englund; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; aggregates; ALS; amyotrophic lateral sclerosis; inclusions; misfolded; vacuolisation; SOD1; transgenic; Pathology; Patologi;

    Sammanfattning : Amyotrophic lateral sclerosis, ALS, is a progressive fatal neurodegenerative disorder affecting motor neurones in motor cortex, brain stem and spinal cord. This inevitably leads to paralysis, respiratory failure and death. LÄS MER

  5. 24. The diagnostic challenge of Parkinsonian syndromes. Clinical and laboratory evaluation

    Författare :Björn Holmberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson s disease; MSA; PSP; autonomic tests; differential diagnosis; levodopa test; NFL; GFAP;

    Sammanfattning : Background: The differentiation between Parkinson's disease (PD), progressive supranuclear palsy (PSP) and multiple system atrophy (MSA) may be difficult, but it is important for prognostic and therapeutic purposes. The aim of this study was to evaluate the differential diagnostic capacity of laboratory tests in a population of patients fulfilling strict clinical criteria for these disorders. LÄS MER

  7. 25. Retinal tumorigenesis and neurodegeneration : strategies to promote tumor cell death and support retinal cell survival to preserve vision

    Författare :Tanzina Mollick; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Our vision is central to our quality of life enabling us to interact with our environment and lead productive lives. The ability to see begins in the retina, one of the paramount features of the eye, as it takes on the task of converting light signals to nerve impulses that are relayed to the visual centers of the brain. LÄS MER