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Visar resultat 1 - 5 av 42 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Astrocytes, reactive gliosis and CNS regeneration

    Författare :Ulrika Wilhelmsson; Göteborgs universitet; []
    Nyckelord :CNS regeneration; astrocytes; reactive gliosis; intermediate filaments;

    Sammanfattning : The regenerative capacity in the adult central nervous system (CNS) is very limited, and the glial cells have been implicated in the inhibition of CNS regeneration. In essentially all CNS pathologies, astrocytes are activated and this process is known as reactive gliosis. LÄS MER

  3. 2. Biochemical and biomechanical modulation of the in vitro retina

    Författare :Linnéa Taylor; Lund Oftalmologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Retina; in vitro; modulation; biomechanics; glutamate; GDNF; stretch; Müller cells; Photoreceptors; gliosis;

    Sammanfattning : The porcine retinal explant culture paradigm offers the possibility to study retinal health, disease and development independently from the surrounding tissues of the eye. Retina-intrinsic effects of molecular and mechanical cues on the isolated retinal sheet can thus be studied with great precision. LÄS MER

  4. 3. Role of intermediate filaments and expression of GFAP and S-100 in astrocytes

    Författare :Mei Ding; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Astrocytes; Gliosis; Kainic acid; Transgenic mouse; S-100; GFAP; Vimentin; RVD regulatory volume decrease ; Taurine; Glutamine; Ascorbate; Glucose;

    Sammanfattning : Astrocytes participate in a variety of important physiologic and pathologic processes in the central nervous system (CNS). One of the most remarkable characteristics of astrocytes is their vigorous response to CNS injuries. LÄS MER

  5. 4. Regeneration in the adult brain after focal cerebral ischemia : exploration of neurogenesis and angiogenesis

    Författare :Wei Jiang; Jukka Jolkkonen; Umeå universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; neurogenesis; angiogenesis; rats; mice; gliosis; BrdU; CBF; protein synthesis; ATP; penumbra; reperfusion; VEGF; 3-D confocal; photothrombosis; MCAO; Medicine; Medicin;

    Sammanfattning : Background: Ischemic stroke ranks as the third major cause of clinical mortality and the leading cause of handicap in adults. Each year, stroke occurs in about 30,000 Swedes. The severity of an acute ischemic stroke depends mainly on the degree and duration of local cerebral blood flow (lCBF) reduction. LÄS MER

  7. 5. Reactive gliosis in the injured brain: The effect of cell communication and Nrf2-mediated cellular defence

    Författare :Heléne Andersson; Göteborgs universitet; []
    Nyckelord :Keywords: astrocyte; gap junction; Hmox1; microglia; Nrf2; Nqo1; oxidative stress; reactive gliosis;

    Sammanfattning : Stroke and other brain injuries trigger an extensive glial cell response referred to as reactive gliosis. Reactive gliosis is characterized by hypertrophic and proliferating astrocytes, proliferating microglia and NG2-positive cells, which eventually form a bordering glial scar around the damaged area. LÄS MER