Sökning: "gliomas"

Visar resultat 1 - 5 av 88 avhandlingar innehållade ordet gliomas.

  1. 1. Studies on the Roles of PDGFRA and EGFR in the Classification and Identification of Therapeutic Targets for Human Gliomas

    Författare :Dongfeng Chen; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gliomas; classification; EGFR; PDGFRA; FGF2; surface expression; cell proliferation;

    Sammanfattning : Glioma is the most common type of primary tumor in the adult central nervous system (CNS). However, the current classification of gliomas is highly subjective and even inaccurate in some cases, which leads to clinical confusion and hinders the development of targeted therapies. LÄS MER

  3. 2. Rule-Based Approaches for Large Biological Datasets Analysis : A Suite of Tools and Methods

    Författare :Marcin Kruczyk; Jan Komorowski; Joaquin Dopazo; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Rough sets; peak finding; gliomas; Alzheimer disease; STAT3; machine learning; feature selection; next generation sequencing;

    Sammanfattning : This thesis is about new and improved computational methods to analyze complex biological data produced by advanced biotechnologies. Such data is not only very large but it also is characterized by very high numbers of features. LÄS MER

  4. 3. Investigations of neural attractor dynamics in human visual awareness

    Författare :David N. Silverstein; Pawel Herman; Martin Ingvar; Karl Friston; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; attractor dynamics; visual awareness; visual perception; visual attention; attentional blink; backward masking; gliomas; brain tumor; white matter; cell assemblies; neocortical model; threat response; fear signaling; amygdala; Biological Physics; Biologisk fysik; Computer Science; Datalogi; Tillämpad matematik och beräkningsmatematik; Applied and Computational Mathematics;

    Sammanfattning : What we see, how we see it and what emotions may arise from stimuli has long been studied by philosophers, psychologists, medical doctors and neuroscientists. This thesis work investigates a particular view on the possible dynamics, utilizing computational models of spiking neural attractor networks. LÄS MER

  5. 4. Gene and Protein Expression in Human Gliomas

    Författare :Oscar Persson; Neurokirurgi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; tumour associated antigen; immunotherapy; glioma; targeted therapy; microarray; proteomics;

    Sammanfattning : The human gliomas are the most common primary brain tumours. They are highly aggressive with a rapid fatal progression for the patient. The invasive growth pattern and inherent resistance to radiation and chemotherapy account for a lack of efficient therapies. LÄS MER

  7. 5. On the Surgical Management of Diffuse Low-Grade Gliomas in Adults

    Författare :Louise Carstam; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Diffuse Low-Grade Gliomas; Surgery; IDH-mutation;

    Sammanfattning : Diffuse low-grade gliomas (dLGG) are rare, slow-growing, yet difficult-to-treat brain tumors that typically affect young to middle-aged adults. The aim of the thesis has been to identify factors affecting management and outcome in terms of symptoms and primarily survival for patients with dLGG. LÄS MER