Sökning: "glioma"

Visar resultat 11 - 15 av 180 avhandlingar innehållade ordet glioma.

1. 11. Molecular epidemiology approach : nested case-control studies in glioma and lymphoid malignancies

   Författare :Florentin Späth; Beatrice S. Melin; Carl Wibom; Ann Sofie Johansson; Ingvar Bergdahl; Ola Landgren; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioma; B cell lymphoma; multiple myeloma; risk; repeated samples; prospective longitudinal study; nested case-control study; circulating sEGFR and sERBB2; circulating immune markers and growth factors; marker disease association; disease progression; NSHDS; Janus; linear mixed modeling; epidemiologi; Epidemiology; Oncology; onkologi;

   Sammanfattning : BACKGROUND: Nested case-control studies aim to link molecular markers with a certain outcome. Repeated prediagnostic samples may improve the evaluation of marker-disease associations. However, data regarding the benefit of repeated samples in such studies are sparse. LÄS MER

3. 12. Molecular Regulation of Vascular Abnormalization and Its Role in Glioma

   Författare :Lei Zhang; Anna Dimberg; Rolf Bjerkvig; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glioma; vasculature; pleiotrophin; PTN; CD93; angiogenesis; GL261; RCAS;

   Sammanfattning : Glioblastoma, grade IV glioma, is the one of the deadliest cancers, with a median survival of only 12-15 months despite aggressive treatment including surgery, chemotherapy and radiation. One hallmark of glioblastoma is the morphological and functional abnormalization of tumor blood vessels. LÄS MER

4. 13. Mesenchymal stromal cells in malignant glioma - Functions and therapeutic potential

   Författare :Andreas Svensson; Neurokirurgi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glioma; glioblastoma; mesenchymal stromal cell; pericyte; immunotherapy; interferon-γ;

   Sammanfattning : The most common malignant brain tumor in adults is a glioma called glioblastoma multiforme (GBM). About 300 persons are diagnosed with GBM every year in Sweden. Unfortunately, it is also the most aggressive brain tumor and as of today, it is not possible to cure it. LÄS MER

5. 14. Challenges in the treatment of malignant glioma with oncolytic adenovirus

   Författare :Johan Rebetz; Lund Pediatrik; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Glioma; Adenovirus; Fiber; Cancer stem cells;

   Sammanfattning : Malignant glioma is a tumor that spreads rapidly throughout brain and is almost impossible to remove completely by surgery. It is resistant to chemo- and radiotherapy and the prognosis is very poor. As a result, there is a desperate need for development of novel therapies against this devastating disease. LÄS MER

7. 15. Qualities in the short life : psychological studies relevant to patient and spouse in malignant glioma

   Författare :Pär Salander; Roger Henriksson; Ullabeth Sätterlund Larsson; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; astrocytoma; communication; coping; defence mechanism; denial; glioma; hope; memory; neuropsychology; quality of life; spouse;

   Sammanfattning : This thesis deals with psychological issues concerning patients with malignant gliomas, and their spouses. There is no known medical cure, and the patients have a limited survival expectancy. Therefore studies evaluating new treatment modes, an overall supportive atmosphere, and attempts to avoid imposing unnessesary strain are necessary. LÄS MER