Sökning: "glial cell activation"
Visar resultat 21 - 25 av 83 avhandlingar innehållade orden glial cell activation.
21. Apoptotic cell death in neural stem cells exposed to toxic stimuli
Sammanfattning : Neural stem cells (NSCs) play an important role in the developing nervous system and in the adult brain, where mitotic regions such as the subventricular zone (SVZ) remain active. In spite of the intense ongoing research on NSCs, we still need to expand the knowledge on biochemical regulation by which NSCs undergo cell death in the course of normal physiology or in response to neurotoxic insults. LÄS MER
22. Apoptotic cell death in neural stem cells exposed to toxic stimuli
Sammanfattning : Neural stem cells (NSCs) play an important role in the developing nervous system and adulthood, where mitotic regions of the brain such as the subventricular zone (SVZ) remain active. In spite of the immense interest in NSC research, little is known about the biochemical regulation by which NSCs undergo cell death in the course of normal physiology or in response to neurotoxic insults. LÄS MER
23. Cell interactions in the CNS and their consequences for neuronal apoptosis
Sammanfattning : The central nervous system consists of an intricate network of neurons and glial cells that depend on reciprocal communication to develop and maintain the vital functions of the brain. if the balance is disturbed by injury or disease, two cell types in particular, microglia and astrocytes, respond by producing factors that help combat the infection or delimit the affected area. LÄS MER
24. Pathological responses of glial cells in spinal cord injury and rheumatoid arthritis
Sammanfattning : Scientists have considered glia as mere passive allies of neurons for a long time. As a consequence, their functions have been greatly underestimated. Major discoveries made in the last three decades have changed our view on glial cells and it is now accepted that they play important roles in health and disease. LÄS MER
25. Neuroprotection in the Injured Spinal Cord : Novel Strategies using Immunomodulation, Stem cell Transplantation and Hyaluronic acid Hydrogel carriers
Sammanfattning : The overall aim of this thesis was to establish strategies to minimize secondary damage to the injured spinal cord. Secondary damage that follows spinal cord injury (SCI) involves inflammatory and excitotoxic pathways. LÄS MER