Sökning: "glial cell activation"

Visar resultat 1 - 5 av 77 avhandlingar innehållade orden glial cell activation.

  1. 1. Glioma as an Ecosystem Studies of Invasion, Onco-miR Addiction and Mast Cell Infiltration

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Jelena Põlajeva; Bengt Westermark; Ingemar Ernberg; [2012]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glioblastoma; mast cell; miR-21; RAP1; CXCL12; SOX2;

    Sammanfattning : Despite recent advances in oncology and extensive research efforts, gliomas remain essentially incurable. Glioblastoma multiforme (GBM, WHO grade IV) is the most common glioma and may arise de novo or progress from a lower-grade lesion. GBM is characterized by invasive growth, aberrant angiogenesis and necrosis. LÄS MER

  2. 2. The role of Nkx proteins neuronal and glial specification

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Cell and Molecular Biology

    Författare :Anna Vallstedt; Karolinska Institutet.; Karolinska Institutet.; [2004]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : During development, different classes of neurons and glia are generated from proliferative progenitor cells lining the ventricles of the brain and the lumen of the spinal cord. A central issue in developmental neuroscience is to understand the mechanisms by which these cells are generated in space and over time. LÄS MER

  3. 3. Finding the ligand : Retinoid receptor activation in the CNS

    Detta är en avhandling från Stockholm : Karolinska Institutet, Department of Cell and Molecular Biology

    Författare :Alexander Mata de Urquiza; Karolinska Institutet.; Karolinska Institutet.; [2001]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Nuclear hormone receptors (NRs) comprise a large family of ligand activated transcription factors, found in vertebrates, arthropods and nematodes. Among the members of the NR family are the receptors for small, lipophilic ligands such as the steroid hormones, vitamins A and D, thyroid hormone oxysterols and bile acids. LÄS MER

  4. 4. The functional organization of nuclear membrane proteins and development of new technology for studies of cell signaling

    Detta är en avhandling från Stockholm : Department of Biochemistry and Biophysics, Stockholm University

    Författare :Ricardo A. Figueroa; Einar Hallberg; Yosef Gruenbaum; [2011]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; biokemi; Biochemistry;

    Sammanfattning : The eukaryotic cell is defined by the nucleus, which is delimited by a double membrane structure termed the nuclear envelope (NE). The NE is implicated in a multitude of different processes, for example chromatin organization. LÄS MER

  5. 5. Roles of Notch signalling in early embryonic development

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Cell and Molecular Biology

    Författare :Heather Main; Karolinska Institutet.; Karolinska Institutet.; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Metazoan embryonic development requires a complex interplay of morphological processes coordinated with self-renewal and differentiation to correctly specify and maintain body cell types in the correct location. Notch signalling is a metazoan specific arbiter of cell fate decision processes, known to control lateral inhibition and asymmetric cell division processes throughout the metazoa and in the development of all metazoan organs. LÄS MER