Sökning: "glenn björk"

Hittade 4 avhandlingar innehållade orden glenn björk.

1. 1. Function of wobble nucleoside modifications in tRNAs of Salmonella enterica Serovar Typhimurium

   Författare :Peng Chen; Glenn R. Björk; Paul Agris; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; tRNA; wobble nucleoside; frameshifting; translation; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

   Sammanfattning : Transfer RNA from all organisms has modified nucleosides and position 34 (the wobble position) is one of the most extensively modified positions. Some wobble nucleoside modifications restrict codon choice (e.g. 5-methylaminomethyl-2-thiouridine, mnm5s2U) while some extend the decoding capacity (e. LÄS MER

3. 2. Frameshifting as a tool in analysis of transfer RNA modification and translation

   Författare :Ramune Leipuviene; Glenn Björk; Diana Downs; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular biology; minor tRNA; frameshifting; suppression; L9; hopping; tRNA thiolation; [Fe-S] cluster; [Fe-S] protein; TtcA; Molekylärbiologi; Molecular biology; Molekylärbiologi; molekylärbiologi; Molecular Biology;

   Sammanfattning : Studies of ribosomal reading frame maintenance are often based on frameshift mutation suppression experiments. In this thesis, suppression of a frameshift mutation in Salmonella enterica serovar Typhimurium by a tRNA and a ribosomal protein are described. LÄS MER

4. 3. Formation of Thiolated Nucleosides in tRNA in Salmonella enterica serovar typhimurium

   Författare :Hans Lundgren; Glenn Björk; Charles Lauhon; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; : tRNA; modified nucleosides; thiolation; sulfur metabolism; Salmonella; Molecular biology; Molekylärbiologi;

   Sammanfattning : The presence and synthesis of transfer RNA (tRNA) is highly conserved in all organisms and a lot of genetic material is dedicated to its synthesis. tRNA contains a large number of modified nucleosides and several diverse functions have been found but much about their function is still unknown. LÄS MER

5. 4. Wobble modifications and other features in transfer RNA important for decoding and reading frame maintenance

   Författare :Joakim Näsvall; Glenn Björk; Michael O'Connor; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Transfer RNA; Modified nucleosides; Decoding; Reading frame maintenance; Molecular biology; Molekylärbiologi;

   Sammanfattning : Transfer RNA (tRNA) is the adaptor molecule responsible for bringing the correct amino acid to the ribosome during protein synthesis. tRNA contains a number of modified nucleosides, which are derivatives of the four normal nucleosides. LÄS MER