Sökning: "glatt muskelceller in vitro"

Hittade 2 avhandlingar innehållade orden glatt muskelceller in vitro.

  1. 1. Mechanosensing in the vascular wall - the role of cellular microdomains in vascular remodeling

    Författare :Sebastian Albinsson; Kärlfysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; tissue culture; Histologi; cytokemi; histokemi; vävnadskultur; cytochemistry; histochemistry; wall stress; shear stress; hypertension; Histology; differentiation; growth; caveolin; smooth muscle; actin; Fysiologi; Cardiovascular system; Kardiovaskulära systemet;

    Sammanfattning : The vascular wall has a remarkable capacity to adapt to mechanical forces exerted by the intraluminal blood pressure and flow. This includes rapid change in contractile tone as well as chronic alteration of vessel structure if the stimulus persists. Stretch of the intact blood vessel wall promotes growth and contractile differentiation. LÄS MER

  3. 2. Cyclic nucleotide signalling systems in vascular smooth muscle cells and immune system cells with special reference to phosphodiesterases PDE3 and PDE4

    Författare :Dag Ekholm; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; HTLV-I; multiple sclerosis; proliferation; phosphorylation; T-lymphocytes; vascular smooth muscle; cloning; protein kinase A; cGMP; cAMP; PDE4; Phosphodiesterase; PDE3; cilostamide; rolipram; Histology; cytochemistry; histochemistry; tissue culture; Histologi; cytokemi; histokemi; vävnadskultur;

    Sammanfattning : The cyclic nucleotide signalling systems are important in vascular smooth muscle and in the immune system, and are of interest from a pharmacological point of view. Drugs which interfere with the cyclic nucleotide levels have profound effects on heart, blood vessels and airways and have actual or potential use in several important diseases, such as heart failure, hypertension, arteriosclerosis, asthma and autoimmune diseases. LÄS MER