Sökning: "gentamicin"
Visar resultat 1 - 5 av 40 avhandlingar innehållade ordet gentamicin.
1. Local Collagen-Gentamicin for Prevention of Sternal Wound Infections
Sammanfattning : In cardiac surgery, sternal wound infection (SWI) continues to be one of the most serious postoperative complications. Coagulase-negative staphylococci (CoNS) have become the most common causative agents of SWI. LÄS MER
2. Pharmacometric Models for Antibacterial Agents to Improve Dosing Strategies
Sammanfattning : Antibiotics are among the most commonly prescribed drugs. Although the majority of these drugs were developed several decades ago, optimal dosage (dose, dosing interval and treatment duration) have still not been well defined. LÄS MER
3. Pharmacokinetic and Pharmacodynamic Modeling of Antibiotics and Bacterial Drug Resistance
Sammanfattning : Exposure to antibiotics is an important factor influencing the development of bacterial resistance. In an era where very few new antibiotics are being developed, a strategy for the development of optimal dosing regimen and combination treatment that reduces the rate of resistance development and overcome existing resistance is of utmost importance. LÄS MER
4. Tracking single molecules in uncharted territory : A single-molecule method to study kinetics in live bacteria
Sammanfattning : The synthesis of proteins, also known as translation, is a fundamental process in every living organism. The steps in the translation of genetic information to functional proteins have been meticulously studied, mostly using in vitro techniques, yielding a detailed model of their mechanisms. LÄS MER
5. Characterization of clinical enterococcal isolates in Swedish hospitals : studies on genetic relatedness and high-level gentamicin resistance
Sammanfattning : During the last few decades, and in parallel with increasing resistance to multiple antibiotics, enterococci have become one of the leading pathogens that cause nosocomial infections. High-level gentamicin resistant (HLGR) enterococci have become frequent. Thus, there are compelling reasons to control the transmission of enterococci with HLGR. LÄS MER