Sökning: "gentamicin treatment"

Visar resultat 1 - 5 av 20 avhandlingar innehållade orden gentamicin treatment.

1. 1. Local Collagen-Gentamicin for Prevention of Sternal Wound Infections

   Författare :Örjan Friberg; Rolf Svedjeholm; Jan Källman; Bo Söderquist; Bengt Gårdlund; Linköpings universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cardiac surgery; Sternal wound infection; Mediastinitis; Antibiotics; Gentamicin; Prophylaxis; Cost-effectiveness; Staphylococcus; Randomised controlled trial; Thoracic surgery; Thoraxkirurgi;

   Sammanfattning : In cardiac surgery, sternal wound infection (SWI) continues to be one of the most serious postoperative complications. Coagulase-negative staphylococci (CoNS) have become the most common causative agents of SWI. LÄS MER

3. 2. Anal Fistula : Aspects of Aetiology, Diagnosis and Prognosis After Surgical Treatment

   Författare :Ulla-Maria Gustafsson; Wilhelm Graf; Torgny Svenberg; Uppsala universitet; []
   Nyckelord :Surgery; anal fistula; risk factors; endoanal advancement flap; anal incontinence; endoanal ultrasound; magnetic resonance imaging; gentamicin-collagen; micro perfusion; laser Doppler flowmetry; Kirurgi;

   Sammanfattning : Patients with idiopathic anal fistula (n=85) were compared with 215 control subjects, matched for age and sex, through a 180-item questionnaire. Obesity, smoking, constipation and bowel symptoms associated with IBS were more common in the patients. LÄS MER

4. 3. Pharmacometric Models for Antibacterial Agents to Improve Dosing Strategies

   Författare :Elisabet I Nielsen; Lena E Friberg; Otto Cars; Mats O Karlsson; Marie Sandström; Alan Forrest; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacometrics; pharmacokinetics; pharmacodynamics; modeling; NONMEM; antibiotics; in vitro; time-kill curve; PK PD indices; gentamicin; aminoglycosides; newborn infants; premature infants; cystatin C; Biopharmacy; Biofarmaci; Pharmacokinetics and Drug Therapy; Farmakokinetik och läkemedelsterapi;

   Sammanfattning : Antibiotics are among the most commonly prescribed drugs. Although the majority of these drugs were developed several decades ago, optimal dosage (dose, dosing interval and treatment duration) have still not been well defined. LÄS MER

5. 4. Pharmacokinetic and Pharmacodynamic Modeling of Antibiotics and Bacterial Drug Resistance

   Författare :Ami Fazlin Syed Mohamed; Lena Friberg; Teresa Dalla Costa; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacometrics; pharmacokinetics; pharmacodynamics; modeling; antibiotics; resistance; combination; Gram-negative bacteria; gentamicin; colistin; meropenem; newborn infants; critically ill patients; Infectious Diseases; Infektionssjukdomar; Pharmaceutical Science; Farmaceutisk vetenskap;

   Sammanfattning : Exposure to antibiotics is an important factor influencing the development of bacterial resistance.  In an era where very few new antibiotics are being developed, a strategy for the development of optimal dosing regimen and combination treatment that reduces the rate of resistance development and overcome existing resistance is of utmost importance. LÄS MER

7. 5. Colorectal cancer : Aspects of staging, treatment, recurrence and survival

   Författare :Åsa Collin; Joakim Folkesson; Wilhelm Graf; Malin Enblad; Marie-Louise Lydrup; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; colorectal cancer; recurrence; survival; staging; postoperative complications; Kirurgi; Surgery; Oncology; Onkologi;

   Sammanfattning : Colorectal cancer is the third most common malignancy in the world, and major breakthroughs have been made regarding both surgical and oncological treatment. Still, postoperative complications, such as perineal infections after abdominoperineal resection (APR), are a major cause of morbidity, and distant recurrence rate is nearly 20%. LÄS MER