Sökning: "genomic variability"

Visar resultat 6 - 10 av 43 avhandlingar innehållade orden genomic variability.

  1. 6. The exploration and evolution of the avian genomic dark matter

    Författare :Valentina Peona; Alexander Suh; Hanna Johannesson; Rachel O'Neill; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; evolutionary genomics; genome assembly; sex chromosomes; birds; satellite DNA; transposable elements; endogenous retroviruses; Biology with specialization in Systematics; Biologi med inriktning mot systematik;

    Sammanfattning : The development and improvement of genome sequencing technologies in the last decade revolutionised the entire field of biology with genome assemblies of virtually any organism. Despite this tremendous progress, complex genomic regions are systematically missing from genome assemblies and form the so-called "genomic dark matter". LÄS MER

  3. 7. Determinants of genomic diversity in the collared flycatcher (Ficedula albicollis)

    Författare :Ludovic Dutoit; Hans Ellegren; Asher Cutter; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; collared flycatcher; Ficedula albicollis; enetic diversity; sexual conflict; effective population size; nucleotide diversity; linked selection; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

    Sammanfattning : Individuals vary from each other in their genetic content. Genetic diversity is at the core of the evolutionary theory. Rooted in a solid theoretical framework developed as early as the 1930s, current empirical observations of genomic diversity became possible due to technological advances. LÄS MER

  4. 8. Implications of Local Puumala Hantavirus Genetics and Epidemiology for Diagnostics and Vaccine Development

    Författare :Patrik Johansson; Fredrik Elgh; Göran Bucht; Detlev Krüger; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Communicable diseases; hantavirus; Puumala virus; nephropathia epidemica; genome sequence; glycosylation; linear DNA vaccine; microarray; identification; genetic variability; Infektionssjukdomar; Infectious diseases; Infektionssjukdomar; medicinsk virologi; Medical Virology;

    Sammanfattning : Puumala viruses, a member of the Hantavirus genus in the Bunyaviridae family, are enveloped by a lipid bilayer and possesses a tripartite single stranded RNA genome with negative polarity. The hantaviruses encode four proteins: a nucleocapsid protein (N), two membrane spanning glycoproteins (GN and GC) and a RNA dependent RNA polymerase (RdRp). LÄS MER

  5. 9. Identification of protein signatures of genomic stability/instability in epithelial cancers

    Författare :Timo Gemoll; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Aneuploidy is a consistent genetic alteration of the cancer genome. At early steps in the sequence of malignant transformation during human tumorigenesis, chromosomal aneuploidies can be the first detectable genetic aberrations found. LÄS MER

  7. 10. Potato mop-top virus: Variability, Movement and Suppression of Host Defence

    Författare :Pruthvi Balachandra Kalyandurg; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Potato mop-top virus (PMTV) causes an economically damaging disease called potato spraing. Despite being reported across the potato growing regions in the world, very little genetic variability has been reported for the virus. LÄS MER