Sökning: "genomic variability"

Visar resultat 11 - 15 av 43 avhandlingar innehållade orden genomic variability.

  1. 11. Impact of genetic variability on early immune reactions following nerve injury

    Författare :Rickard P F Lindblom; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Injury to the central nervous system (CNS) is frequently associated with significant morbidity, in worst case mortality. This in turn leads to considerable disease burden for the individual and also for society. LÄS MER

  3. 12. On gastrointestinal viral infections

    Författare :Thomas Beck-Friis; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; norovirus; rotavirus; SARS-CoV-2; gastroenteritis; diagnosis; elderly; epidemiology; humidity; COVID-19; genomic structural variation;

    Sammanfattning : Gastrointestinal viral infections cause considerable morbidity and mortality worldwide. Many factors influencing clinical presentation, disease severity, epidemiology, and transmission are not fully understood. LÄS MER

  4. 13. Meiotic Recombination in Human and Dog : Targets, Consequences and Implications for Genome Evolution

    Författare :Jonas Berglund; Matthew Webster; Kerstin Lindblad-Toh; Leif Andersson; Nadia Singh; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; recombination; biased gene conversion; CpG island; copy number variation; substitutions; methylation; Bioinformatics; Bioinformatik; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution; Molekylär genetik; Molecular Genetics;

    Sammanfattning : Understanding the mechanism of recombination has important implications for genome evolution and genomic variability. The work presented in this thesis studies the properties of recombination by investigating the effects it has on genome evolution in humans and dogs. LÄS MER

  5. 14. Studies of Genome Diversity in Bartonella Populations : A journey through cats, mice, men and lice

    Författare :Hillevi Lina Lindroos; Siv G. E. Andersson; Richard Birtles; Uppsala universitet; []
    Nyckelord :Biology; Bartonella; genome content; genome rearrangement; gene expression; phage; microarray; PFGE; MLST; Biologi;

    Sammanfattning : Bacteria of the genus Bartonella inhabit the red blood cells of many mammals, including humans, and are transmitted by blood-sucking arthropod vectors. Different species of Bartonella are associated with different mammalian host species, to which they have adapted and normally do not cause any symptoms. LÄS MER

  7. 15. The immunoglobulin genes in an Actinopterygian fish, the Siberian sturgeon (Acipenser baeri)

    Författare :Mats Lundqvist; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Immunoglobulin genes; gene organization; transmembrane TM ; comparative immunology; Siberian sturgeon Acipenser baerii ; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; Molecular Immunology; molekylär immunologi;

    Sammanfattning : Characterization of the immunoglobulin (Ig) light (L) and heavy (H) chain genes from the Siberiansturgeon, Acipenser baeri, revealed an Ig structure simhar to the IgM elass of mammals. The serumforms of the sturgeon Ig are tetrameric and dimeric. LÄS MER