Sökning: "genome-wide"
Visar resultat 6 - 10 av 522 avhandlingar innehållade ordet genome-wide.
6. The Epigenome of Multiple Myeloma : From genome-wide analysis to pharmacological manipulation
Sammanfattning : Nowadays epigenetic dysregulation is known to play a crucial role in virtually all cancers. In multiple myeloma (MM), an extensively heterogeneous malignancy, the key common feature among patients is the gene silencing imposed by the PRC2 complex through the addition of H3K27me3. LÄS MER
7. Genome-wide analysis of KMT2A-rearranged leukemia
Sammanfattning : .... LÄS MER
8. Theoretical studies of Membrane Proteins : Properties, Prediction Methods and Genome-wide analysis
Sammanfattning : Membrane proteins are a large and important class of proteins. They are responsible for several of the key functions in a living cell, e.g. transport of nutrients and ions, cell-cell signaling, and cell-cell adhesion. LÄS MER
9. Novel Bioinformatics Applications for Protein Allergology, Genome-Wide Association and Retrovirology Studies
Sammanfattning : Recently, the pace of growth in the amount of data sources within Life Sciences has increased exponentially until pose a difficult problem to efficiently manage their integration. The data avalanche we are experiencing may be significant for a turning point in science, with a change of orientation from proprietary to publicly available data and a concomitant acceptance of studies based on the latter. LÄS MER
10. Aneuploidy compensatory mechanisms and genome-wide regulation of gene expression in Drosophila melanogaster
Sammanfattning : Stimulation or repression of gene expression by genome-wide regulatory mechanisms is an important epigenetic regulatory function which can act to efficiently regulate larger regions or specific groups of genes, for example by compensating for loss or gain of chromosome copy numbers. In Drosophila melanogaster there are two known chromosome-wide regulatory systems; the MSL complex, which mediates dosage compensation of the single male X-chromosome and POF, which stimulates expression from the heterochromatic 4th chromosome. LÄS MER