Sökning: "genome stability"

Visar resultat 16 - 20 av 113 avhandlingar innehållade orden genome stability.

1. 16. Ljungan Virus Replication in Cell Culture

   Författare :Jens-Ola Ekström; Kjell Edman; Glyn Stanway; Högskolan i Kalmar; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Ljungan virus; picornavirus; parechovirus; 5 - RACE; 5 -end; infectious cDNA clone; real time PCR; virus purification; virion stability; disinfection; aphthovirus-like 2A; Virology; Virologi; Mikrobiologi; Microbiology;

   Sammanfattning : Ljungan virus (LV) is a recently identified picornavirus of the genus Parechovirus. LV has been isolated from voles trapped in Sweden and also in the United States. LV infected small rodents may suffer from diabetes type 1 and type 2 like symptoms, myocarditis and encephalitis. LÄS MER

3. 17. Characterization of the inner nuclear membrane protein Samp1, during interphase and mitosis

   Författare :Veronica J. Larsson; Einar Hallberg; Katharine S. Ullman; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Samp1; LINC complex; nuclear lamina; MCLIP; nuclear envelope; spindle assembly; spindle stability; k-fiber; gamma tubulin; Aurora B; Haus6; Augmin; neurokemi med molekylär neurobiologi; Neurochemistry with Molecular Neurobiology;

   Sammanfattning : The nucleus, a hallmark in eukaryotic cells, contains the genome separating it from molecules in the cytoplasm. The nucleus is surrounded by a nuclear envelope consisting of two concentric membranes, the outer nuclear membrane and the inner nuclear membrane, the nuclear lamina and nuclear pore complexes. LÄS MER

4. 18. Adaptive divergence in fission yeast : From experimental evolution to evolutionary genomics

   Författare :Sergio Ivan Tusso Gomez; Jochen B.W. Wolf; Simone Immler; Roger K. Butlin; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; adaptation; divergence; selection; experimental evolution; genomics; genome evolution; population genetics; fission yeast; phenotypic variation; Biology with specialization in Evolutionary Genetics; Biologi med inriktning mot evolutionär genetik;

   Sammanfattning : How adaptation and population differentiation occur is fundamental to understand the origin of biodiversity. Work in speciation alongside the increased ease of generating genomic data have allowed the exploration of genomic changes relevant to adaptation. LÄS MER

5. 19. Tumor Suppressor function of the deubiquitinating enzyme BAP1 and its substrate gamma-tubulin In regulation of cell cycle and genome stability

   Författare :Reihaneh Zarrizi; Avdelningen för translationell cancerforskning; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : In normal cells, the cell cycle is controlled by a complex series of signalling pathways by which a cell grows, replicates its DNA and divides. The critical task of the cell cycle is to ensure that DNA is faithfully replicated and that identical chromosomal copies are distributed equally to two daughter cells during mitosis with the help of the mitotic spindle. LÄS MER

7. 20. Mapping the genome and characterization of an acetyltransferase of Trypanosoma cruzi

   Författare :Stephen O Ochaya; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Trypanosoma cruzi; Chagas´disease; karyotyping; genomic; acetyltransferase;

   Sammanfattning : Trypanosoma cruzi (T.cruzi) is a flagellate protozoan parasite that causes Chagas' disease and is most common in Latin American countries. The disease currently infects over 13 million persons and about 100 million more are at risk. Despite basic research for many years, there is neither a vaccine nor useful drugs available to combat the disease. LÄS MER