Sökning: "genome sequence"

Visar resultat 1 - 5 av 432 avhandlingar innehållade orden genome sequence.

  1. 1. Guardians of the genome : Connecting chromatin structure and genome integrity in Saccharomyces cerevisiae

    Författare :Stefanie Lena Bauer; Stefan U. Åström; Brian Luke; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; molekylär biovetenskap; Molecular Bioscience;

    Sammanfattning : Branched DNA structures arise during recombination and during other DNA repair processes such as repair of stalled replication forks. One branched structure, the Holliday Junction (HJ), is a four-way junction that can connect sister chromatids or homologous chromosomes. We show a physical interaction between the HJ-cleaving enzyme Yen1 and Uls1. LÄS MER

  3. 2. Studies of Genome Diversity in Bartonella Populations : A journey through cats, mice, men and lice

    Författare :Hillevi Lina Lindroos; Siv G. E. Andersson; Richard Birtles; Uppsala universitet; []
    Nyckelord :Biology; Bartonella; genome content; genome rearrangement; gene expression; phage; microarray; PFGE; MLST; Biologi;

    Sammanfattning : Bacteria of the genus Bartonella inhabit the red blood cells of many mammals, including humans, and are transmitted by blood-sucking arthropod vectors. Different species of Bartonella are associated with different mammalian host species, to which they have adapted and normally do not cause any symptoms. LÄS MER

  4. 3. Phylogeny and topological incongruence in the Rubioideae (Rubiaceae)

    Författare :Olle Thureborn; Catarina Rydin; Sylvain G. Razafimandimbison; Niklas Wikström; Michael D. Pirie; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Anthospermeae; cytonuclear discordance; gene trees; incomplete lineage sorting; incongruence; mitochondrial genome; nuclear genome; phylogenomics; phylogeny; plastid genome; Rubiaceae; Rubioideae; species trees; Plant Systematics; växtsystematik;

    Sammanfattning : The work with this thesis has focused on evolutionary relationships in the Rubioideae, the most species-rich subfamily of the large and diverse coffee family (Rubiaceae). Despite considerable efforts during the last decades, uncertainty regarding several relationships in this group has remained, either as a result of unconvincing statistic support, incongruent results, or insufficient taxon sampling. LÄS MER

  5. 4. Genome sequencing. Analysis of pathogenicity factors in hereditary and bacterial diseases

    Författare :Joakim Westberg; KTH; []
    Nyckelord :genome sequencing; DNA sequencing; dye-terminator; solid-phase; de novo mutation detection; Mycoplasma mycoides subsp. mycoides SC; mycoplasma; CBPP; properdin; insertion sequence; ISMmy1;

    Sammanfattning : With a metal removal process based on precipitation aimed atthe purification of pulping effluent as a starting point, theinfluence of carboxylic acids on calcium carbonateprecipitation has been studied. The chosen carboxylic acids canact as more or less strong complexing agents for aqueouscalcium, just as many compounds found in pulping liquors. LÄS MER

  7. 5. Hidden patterns that matter : statistical methods for analysis of DNA and RNA data

    Författare :Therese Kellgren; Patrik Rydén; Sara Sjöstedt de Luna; Rebecka Jörnsten; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Genome; Next-generation sequence; statistics; microarrays; bacteria; antibiotic resistance; inherited diseases; Co-expression networks; centralization within subgroups;

    Sammanfattning : Understanding how the genetic variations can affect characteristics and function of organisms can help researchers and medical doctors to detect genetic alterations that cause disease and reveal genes that causes antibiotic resistance. The opportunities and progress associated with such data come however with challenges related to statistical analysis. LÄS MER