Sökning: "genome duplication"
Visar resultat 16 - 20 av 66 avhandlingar innehållade orden genome duplication.
16. Investigation of Mechanics of Mutation and Selection by Comparative Sequencing
Sammanfattning : The process of evolution is of both scientific and medical interest. This thesis presents several studies using complete genomic reference sequences, comparative genomic data, and intraspecific diversity data to study the two key processes of evolution: mutation and selection. LÄS MER
17. Bio-inspired crossover and a model of neuronal reprogramming
Sammanfattning : Bio-inspired crossover:Natural genomes are affected by various kinds of mutations, manifesting as variations in the genome. This includes modifications to individual base pairs (single nucleotide polymorphism, SNP), but also short insertions and deletions (indels), and variations in the position (translocations) or multiplicity (copy number variations) of genetic sequences. LÄS MER
18. Evolution of the Neuropeptide Y System in Vertebrates with Focus on Fishes
Sammanfattning : Gene families in vertebrates often contain more dulicates (paralogs) than in invertebrates. This has been attributed to genome duplications, i.e., tetraploidizations. LÄS MER
19. Evolution of acetylcholine receptors and study of the anatomy of the mouse brain reward system
Sammanfattning : This thesis work is divided in two parts. In the first part, I make use of the transgenic TRPV1-Cre mouse line as a tool to investigate the midbrain ventral tegmental area (VTA). LÄS MER
20. MHC diversity and expression in a songbird : Temporal and transgenerational variation
Sammanfattning : The immune system is of central importance to clear-off pathogens in order to keep an organism healthy. In vertebrates, the Major Histocompatibility Complex (MHC) is a genomic region that holds key genes involved in adaptive immunity and in particular in the antigen presenting process. LÄS MER