Sökning: "genetically engineered T cells"
Visar resultat 1 - 5 av 9 avhandlingar innehållade orden genetically engineered T cells.
1. The Multiple Faces of Genetically-Modified T Cells : Potential Applications in Therapy
Sammanfattning : In this PhD thesis the potential of T-cells as therapy for disease are explored. The applications of genetically modified T-cells for treatment of cancer and autoimmune disease; the functionality and optimal activation of T-cells are discussed. LÄS MER
2. Characterization and targeting of leukemia propagating cells
Sammanfattning : Patients with hematopoietic malignancies have a large, unmet medical need. Allogeneic hematopoietic stem cell transplantation remains the only curative option, but many patients are not eligible for such treatment. LÄS MER
3. CNS-Targeted Cell Therapy for Multiple Sclerosis
Sammanfattning : Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system (CNS). In the current thesis, we have preformed an immunological investigation of patients with MS and developed an immunosuppressive cell therapy that could be beneficial for these patients. LÄS MER
4. Immunohistochemical study of rats receiving peripheral immunization with IFNg transfected glioma cells
Sammanfattning : Malignant glioma is, with rare exceptions in younger adults, an uncurable brain tumor, as very few survive more than 1-2 years after diagnosis. Despite advances in recent years, current treatments such as surgery, radiotherapy and chemotherapy only prolongs the life of the patients. LÄS MER
5. Human immune responses to SARS-Cov-2 and influenza A virus infection : from myeloid-derived suppressor cells and T cell functions to antibody responses
Sammanfattning : Acute respiratory viral infections are the most frequent reason for medical consultations in the world. They cause substantial illness and death every year, especially in young children, the immunocompromised and the elderly, with a large span of disease severity ranging from mild to fatal. LÄS MER
