Sökning: "genetic"

Visar resultat 21 - 25 av 4257 avhandlingar innehållade ordet genetic.

1. 21. Genetic studies of craniosynostosis with focus on syndromic forms

   Författare :Alexandra Topa; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cranial; suture; genetic; diagnostic; next generation sequencing;

   Sammanfattning : Craniosynostosis (CS) represents the premature closure of skull sutures and affects ~1 in 2500 children. Untreated CS can lead to significant complications in craniofacial and psychomotor development. The only treatment available is surgical and requires access to highly specialized healthcare. LÄS MER

3. 22. Chosen Children? : An empirical study and a philosophical analysis of moral aspects of pre-implantation genetic diagnosis and germ-line gene therapy

   Författare :Kristin Zeiler; Lennart Nordenfelt; Gunilla Tegern; Karin Sporre; Åge Wifstaad; Linköpings universitet; []
   Nyckelord :HUMANIORA; HUMANITIES; Empirical ethics; pre-implantation genetic diagnosis; germ-line gene therapy; qualitative research; philosophical analysis; medical progress; genetic disease; choice; auautonomous; ambivalence; trust; genetic identity; Genterapi; biologisk etik; medicinsk etik; preimplanatorisk genetisk diagnostik; Philosophy subjects; Filosofiämnen;

   Sammanfattning : With pre-implantation genetic diagnosis (PGD), genetic testing and selective transfer of embryos is possible. In the future, germ-line gene therapy (GLGT) applied to embryos before implantation, in order to introduce missing genes or replace mutant ones, may be possible. LÄS MER

4. 23. Genetic analysis of murine malaria

   Författare :Susana Campino; Dan Holmberg; Nils Lycke; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Malaria; genetic analysis; Plasmodium; wild derived inbred strains; loci; cerebral malaria; hyperparasitaemia.; Genetik; Clinical genetics; Klinisk genetik; genetik; Genetics;

   Sammanfattning : Malaria, an infectious disease caused by Plasmodium parasites, is one of the major world-scale health problems. Despite the efforts aimed at finding an effective way to control the disease, the success has been thwarted by the emergence of parasite drug resistance and mosquito resistance to insecticides. LÄS MER

5. 24. Genetic Heteroscedasticity for Domestic Animal Traits

   Författare :Majbritt Felleki; Erling Strandberg; Lars Rönnegård; Ole Fredslund Christensen; Högskolan Dalarna; Sveriges lantbruksuniversitet; []
   Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Quantitative genetics; genetic heteroscedasticity of residuals; genetic heterogeneity of environmental variation; genetic heterogeneity of residual variance; double hierarchical generalized linear models; teat count in pigs; litter size in pigs; milk yield in cows; somatic cell count in cows; Complex Systems – Microdata Analysis; Komplexa system - mikrodataanalys;

   Sammanfattning : Animal traits differ not only in mean, but also in variation around the mean. For instance, one sire’s daughter group may be very homogeneous, while another sire’s daughters are much more heterogeneous in performance. The difference in residual variance can partially be explained by genetic differences. LÄS MER

7. 25. Genetic variation in structured populations

   Författare :Marina Rafajlovic; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; genetic variation; varying population size; effective population size; mutation; recombination; migration; multiple paternity; geographic structure; tests of neutrality; gene tree; species tree;

   Sammanfattning : It is widely acknowledged that the process of speciation in the presence of gene flow between different ecotypes is common in nature. However, the mechanisms underlying speciation are not understood. LÄS MER