Sökning: "genetic recombination"

Visar resultat 1 - 5 av 147 avhandlingar innehållade orden genetic recombination.

1. 1. Advances in studying the role of genetic divergence and recombination in adaptation in non-model species

   Författare :Ramprasad Neethiraj; Christopher Wheat; Sören Nylin; Mathieu Joron; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Recombination; Genetic divergence; Lepidoptera; Genetic variation; Genetic diversity; Holocentric chromosomes; cis-regulatory variation; Allele-specific expression; populationsgenetik; Population Genetics;

   Sammanfattning : Understanding the role of genetic divergence and recombination in adaptation is crucial to understanding the evolutionary potential of species since they can directly affect the levels of genetic variation present within populations or species. Genetic variation in the functional parts of the genome such as exons or regulatory regions is the raw material for evolution, because natural selection can only operate on phenotypic variation already present in the population. LÄS MER

3. 2. Genetic variation in structured populations

   Författare :Marina Rafajlovic; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; genetic variation; varying population size; effective population size; mutation; recombination; migration; multiple paternity; geographic structure; tests of neutrality; gene tree; species tree;

   Sammanfattning : It is widely acknowledged that the process of speciation in the presence of gene flow between different ecotypes is common in nature. However, the mechanisms underlying speciation are not understood. LÄS MER

4. 3. Genetic Variation in Mhc Class II B in Atlantic Salmon: Evolutionary and Ecological Perspectives

   Författare :Åsa Langefors; Biodiversitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; recombination; genetic variation; Mhc class II B; Atlantic salmon; evolution; population genetics; Animal ecology; Djurekologi;

   Sammanfattning : The Major Histocompatibility Complex (Mhc) genes are crucial for the recognition of self and non-self peptides by the immune defence system. They are extremely variable in most studied vertebrate species. I have studied the extent and the importance of Mhc variation in Atlantic salmon (Salmo salar), mainly from the Baltic Sea. LÄS MER

5. 4. Environmental Contaminants, Recombination and Cancer : Investigations on the molecular mechanisms of spontaneous and induced recombination in the hprt gene of Chinese hamster cells

   Författare :Thomas Helleday; Mark Meuth; Stockholms universitet; []
   Nyckelord :toxikologisk genetik; Genetic Toxicology;

   Sammanfattning : Recombination results in rearrangement of the genetic material contained in the chromosomes inherited from the mother and father and this process is also involved in repairing damage to the genome. Occasionally, the machinery that performs recombination malfunctions and this may lead to illegitimate recombination events which inactivate tumor suppressor genes or activate protooncogenes. LÄS MER

7. 5. Genetic variability of hepatitis B virus in chronic infection

   Författare :Charles Hannoun; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; hepatitis B virus; mutation; genotype; phylogeny; ; Recombination; coinfection; interferon; response;

   Sammanfattning : Chronic hepatitis B is a major health problem, and may lead to cirrhosis and hepatocellular carcinoma. The liver damage in hepatitis B virus (HBV) infection is considered to be a result of the immune response, and not a cytopathic effect of the virus itself. LÄS MER