Sökning: "genetic linkage"

Visar resultat 11 - 15 av 291 avhandlingar innehållade orden genetic linkage.

1. 11. Advances in studying the role of genetic divergence and recombination in adaptation in non-model species

   Författare :Ramprasad Neethiraj; Christopher Wheat; Sören Nylin; Mathieu Joron; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Recombination; Genetic divergence; Lepidoptera; Genetic variation; Genetic diversity; Holocentric chromosomes; cis-regulatory variation; Allele-specific expression; populationsgenetik; Population Genetics;

   Sammanfattning : Understanding the role of genetic divergence and recombination in adaptation is crucial to understanding the evolutionary potential of species since they can directly affect the levels of genetic variation present within populations or species. Genetic variation in the functional parts of the genome such as exons or regulatory regions is the raw material for evolution, because natural selection can only operate on phenotypic variation already present in the population. LÄS MER

3. 12. Genetic linkage and association studies in celiac disease: discoveries from whole genome analysis

   Författare :Svetlana Adamovic; Göteborgs universitet; []
   Nyckelord :Celiac Disease; genome-wide scan; linkage; association; GWAS; complex disease; autoimmune; 5q31-33; HLA; IL2 IL21;

   Sammanfattning : Celiac Disease (CD) or Gluten Sensitive Enteropathy (GSE) is a life-long disorder. It is characterized by inflammation in the small intestine of genetically predisposed individuals caused by inappropriate immune response to gluten, a protein enriched in some of our common grains (wheat, rye and barley). LÄS MER

4. 13. Genetic studies of schizophrenia

   Författare :Eva Lindholm; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; Schizophrenia; complex diseases; mitochondria; large pedigree; linkage analysis; Genetik; Clinical genetics; Klinisk genetik; Genetics; genetik;

   Sammanfattning : The prevalence of schizophrenia is about 1% throughout the world. The disease is characterized by symptoms such as hallucinations, delusions and bizarre behavior. A genetic contribution to the disease was previously shown through epidemiological studies. The mitochondrial DNA was sequenced in four schizophrenic patients. LÄS MER

5. 14. Genetic studies of stroke in Northern Sweden

   Författare :Sofie Nilsson Ardnor; Dan Holmberg; Jan Hillert; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; stroke; linkage; genome wide scan; susceptibility loci; association; candidade gene; PDE4D; PIK3R1; extended pedigree; Medical genetics; Medicinsk genetik;

   Sammanfattning : Stroke is a common disorder of later life with a complex etiology, including both environmental and genetic risk factors. The inherited predisposition is challenging to study due to the complexity of the stroke phenotype. LÄS MER

7. 15. Two contributions to genetic linkage analysis

   Författare :Staffan Nilsson; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

   Sammanfattning : .... LÄS MER