Sökning: "gene upregulation"

Visar resultat 1 - 5 av 232 avhandlingar innehållade orden gene upregulation.

  1. 1. Gene expression in carcinogenesis

    Författare :Heléne Fischer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : It is important to understand the processes of carcinogenesis and to find out which genes are involved . One way to study the process on a molecular basis is to identify differences in gene expression. LÄS MER

  3. 2. Adenovirus-mediated Gene Therapy of Prostate Cancer

    Författare :Angelika Danielsson; Mangus Essand; Thomas H. Tötterman; Gunnel Hallden; Uppsala universitet; []
    Nyckelord :adenovirus; adenoviral vector; oncolytic virus; gene therapy; prostate cancer; PEGylation; HDAC inhibitor; whole blood model; whole blood neutralization assay; MEDICINE; MEDICIN; Klinisk immunologi; Clinical Immunology; Molekylär genetik; Molecular Genetics;

    Sammanfattning : Adenovirus-mediated gene therapy is a potential complement to standard cancer treatments. Advantages are that vectors can be used to target tumors and that replicating viruses lead to increased therapeutic dosage. LÄS MER

  4. 3. Gene and pathway associations in neurodevelopmental disorders

    Författare :Mitra Etemadikhah; Lars Feuk; Kristiina Tammimies; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Gene expression analyses; Neurodevelopmental disorders; Intellectual disability; Schizophrenia;

    Sammanfattning : Neurodevelopmental disorders are complex and heterogenous disorders affecting brain development. In this thesis, we study intellectual disability (ID) and schizophrenia, and we applied genomic, transcriptomic, and proteomic techniques to identify and further investigate candidate variants and important genes and pathways involved in pathology of these two disorders. LÄS MER

  5. 4. Signal Transduction and Gene Regulation in Cerebral Arteries Following Ischemia

    Författare :Petter Vikman; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Naturvetenskap; Cardiovascular system; stroke; molecular investigation; gene expression; Mitogen Activated Protein Kinases; Natural science; Kardiovaskulära systemet; cerebral arteries;

    Sammanfattning : The thesis consideres the molecular events that take place in the cerebral arteries following a stroke. The degree and temporal course of reperfusion following a stroke is pivotal for the survival of the neuronal tissue in the penumbra. LÄS MER

  7. 5. Cellulose synthases in Populus- identification, expression analyses and in vitro synthesis

    Författare :Soraya Djerbi; Tuula Teeri; Petter Gustafsson; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; cellulose synthase; Populus; secondary cell wall; gene upregulation; cell suspension culture; stationary phase; Bioengineering; Bioteknik;

    Sammanfattning : Cellulose is a biopolymer of great relevance in the plant cell walls, where it constitutes the most important skeletal component. Cellulose is also an important raw material in the pulp- and paper, forest, and textile industries, among others. LÄS MER