Sökning: "gene regulation"

Visar resultat 11 - 15 av 1808 avhandlingar innehållade orden gene regulation.

  1. 11. RhoGTPase Signaling in Cell Polarity and Gene Regulation

    Författare :Ann-Sofi Johansson; Pontus Aspenström; Johan Lennartsson; Christer Larsson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; RhoGTPase; Par6; cell polarity; aPKC; epithelial cell; PDGF; gene regulation; microarray; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi;

    Sammanfattning : RhoGTPases are proteins working as molecular switches as they bind and hydrolyze GTP. They are in their active conformation when GTP is bound and are then able to interact with their effector proteins, which relay the downstream signaling. When the GTP is hydrolyzed to GDP, the RhoGTPase is inactivated. LÄS MER

  3. 12. Thioredoxins and gene regulation in the Drosophila germline

    Författare :Malin J. Svensson; Jan Larsson; David Roberts; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Drosophila; thioredoxin; sex-specific; Pof; chromosome 4; gene regulation; kromosom 4; genreglering; Drosophila; thioredoxin; könsspecifik; Pof; Molecular biology; Molekylärbiologi;

    Sammanfattning : Spermatogenesen är i många organismer en av de mest dramatiska förvandlingar som en cell kan genomgå – en vanlig, rund, diploid cell omvandlas till en nålformad, haploid cell med ett tätt packat cellmaskineri. I bananfluga, Drosophila melanogaster, innebär denna process flera karaktäristiska stadier. LÄS MER

  4. 13. Gene regulation by Early B-cell Factor (EBF)

    Författare :Peter Åkerblad; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; Immunology; B-lymphocytes; Differentiation; Transcription; EBF; Gene regulation; transplantation; Immunologi; serologi;

    Sammanfattning : In this study we aimed at defining genes that are controlled by Early B-cell Factor (EBF), that could explain the severe block in B-cell development observed in EBF-/- mice. The fact that EBF appears to be important for the transcriptional control of genes encoding proteins in the pre-B and B-cell receptor complex implied to us that EBF could be a common regulator of other components in the pre-B and B-cell receptor. LÄS MER

  5. 14. TARP Promoter-Based Prostate Cancer Gene Therapy : From Development to Application

    Författare :Wing-Shing Cheng; Magnus Essand; Thomas H. Tötterman; Cecilia Lundberg; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Genetic engineering; TARP; PPT; TSTA; promoter; gene regulation; prostate specificity; hormone- independent; adenovirus; prostate cancer; gene therapy; conditionally replicating adenovirus; Genteknik; Genetic engineering including functional genomics; Genteknik inkl. funktionsgenomik;

    Sammanfattning : Prostate cancer is one leading cause of cancer-related death among men in Western countries. The standard therapies for localized prostate cancer include radical prostatectomy and radiation therapy. Such measures are relatively effective in the short term, but many patients ultimately relapse. LÄS MER

  7. 15. Systems biology techniques show high prevalence of post-translational regulation in the cyanobacterium Synechocystis PCC 6803

    Författare :Jan Karlsen; Elton Paul Hudson; Martin Hagemann; KTH; []
    Nyckelord :systems biology; sustainable development; omics; ribosome profiling; RNA sequencing; proteomics; genetic engineering; bioproduction; cyanobacteria; gene regulation; metabolism; translational regulation; post-translational regulation; bioinformatics; Bioteknologi; Biotechnology;

    Sammanfattning : Earth's climate has been upset by carbon dioxide (CO2) emissions from human activities and the use of fossil resources. To prevent catastrophic events on the environment and on civilizations, we urgently need to develop alternative solutions that utilize renewable resources. LÄS MER