Sökning: "gene polymorphism"

Visar resultat 1 - 5 av 455 avhandlingar innehållade orden gene polymorphism.

  1. 1. Coffee and gene interaction. The effect on methionine and lipid metabolism

    Författare :Elisabeth Strandhagen; Göteborgs universitet; []
    Nyckelord :coffee; homocysteine; cholesterol; folate; pyridoxine; MTHFR; APOE; gene; polymorphism; interaction;

    Sammanfattning : Background: Different dietary factors influence the risk of coronary heart disease (CHD), most likely in an interaction with genetic polymorphisms. The knowledge about such interactions is insufficient. Some observational studies have shown an association between coffee and CHD, others have not. Coffee consumption affects some CHD risk factors, e. LÄS MER

  3. 2. Osteoporosis in elderly women; Bone traits, fracture and the PTH gene complex

    Författare :Max Tenne; Ortopedi - klinisk och molekylär osteoporosforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; osteoporosis; fracture; parathyroid hormone; gene; polymorphism; dual energy X-ray absorptiometry; bone mineral density; hip strength analysis;

    Sammanfattning : Background: Fragility fractures are a major health problem world wide and the numbers are growing due to ageing populations. Early identification of individuals at risk for osteoporosis and fracture, enabling preventive measures and treatment is essential. LÄS MER

  4. 3. Genetic diversity of the heat labile (LT) and heat stable (ST) toxins of human enterotoxigenic Escherichia coli (ETEC): New insights into polymorphism, regulation, and gene transcription

    Författare :Enrique Joffre; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ETEC; diversity; bacterial enterotoxins; polymorphism; gene regulation; gene transcription; Diarrhoeal disease; bacterial infection;

    Sammanfattning : Infection with enterotoxigenic Escherichia coli (ETEC) is a leading cause of diarrhea in children in developing countries and travelers to endemic regions. ETEC is a diverse pathogen, with a wide range of virulence factors including enterotoxins and more than 25 identified colonization factors (CFs). LÄS MER

  5. 4. Gene conversion of the mouse MHC class II

    Författare :Kari Högstrand; Ulf Gyllensten; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MHC; H2; gene conversion; evolution; polymorphism; Immunology; Immunologi; immunologi; Immunology;

    Sammanfattning : The major histocompatibility complex (MHC) is the most polymorphic vertebrate gene loci known to exist. Gene products of the MHC are responsible for presentation of antigen derived peptides to T cells of the immune system, which thereby become activated and involved in the elimination of particles recognised as non-self. LÄS MER

  7. 5. Genetic Variability in Human Bone Phenotypes : The Vitamin D Receptor Gene and the Estrogen Receptor-α Cofactor RIZ Gene

    Författare :Elin Grundberg; Andreas Kindmark; Östen Ljunggren; Helena Brändström; André G. Uitterlinden; Uppsala universitet; []
    Nyckelord :Medicine; Bone mineral density; candidate gene approach; polymorphism; the vitamin D receptor; the estrogen receptor α; RIZ1; cofactor; allelic imbalance; Medicin;

    Sammanfattning : Important candidate genes to human bone phenotypes are those involved in the regulation of hormonal action, such as the vitamin D receptor (VDR) and the estrogen receptor-α (ERα) genes and their cofactors. RIZ1 is a specific ERα cofactor proved to strongly enhance the function of the ERα. LÄS MER