Sökning: "gene expression profiling"

Visar resultat 6 - 10 av 265 avhandlingar innehållade orden gene expression profiling.

1. 6. Gene Expression Profiling of Human Atherosclerosis

   Författare :Sara Hägg; Linköpings universitet; []
   Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

   Sammanfattning : Atherosclerosis is the main underlying cause of coronary artery disease (CAD) and stroke. These two diseases are leading causes of death in the developed world. The socio-economical cost for treatments and absence of work is enormous. Recent numbers from the US show no tendency of decline in the spread of atherosclerosis. LÄS MER

3. 7. Global Profiling of Host Cell Gene Expression During Adenovirus Infection

   Författare :Fredrik Granberg; Hongxing Zhao; Ulf Pettersson; Richard Roberts; Uppsala universitet; []
   Nyckelord :Genetic engineering; Adenovirus; Microarray; Gene expression; Host-virus interaction; Genteknik;

   Sammanfattning : To investigate mechanisms involved in virus-host interactions, global changes in host gene expression were examined during infection with adenovirus type 2 (Ad2) using cDNA microarray technology. In paper I and II, transcriptional changes in HeLa cells were investigated during the early and late phase of infection, respectively. LÄS MER

4. 8. Gene Expression Profiling of Human Atherosclerosis

   Författare :Sara Hägg; Johan Björkegren; Jesper Tegnér; Josefin Skogsberg; Olle Melander; Linköpings universitet; []
   Nyckelord :NATURAL SCIENCES; NATURVETENSKAP;

   Sammanfattning : Atherosclerosis is a progressive inflammatory disease that causes lipid accumulation in the arterial wall, leading to the formation of plaques. The clinical manifestations of plaque rupture—stroke and myocardial infarction—are increasing worldwide and pose an enormous economic burden for society. LÄS MER

5. 9. Subtracted Approaches to Gene Expression Analysis in Atherosclerosis

   Författare :Stina Boräng; KTH; []
   Nyckelord :Representational Difference Analysis; atherosclerosis; gene expression profiling;

   Sammanfattning : Gene expression analysis has evolved as an extensive toolfor elucidation of various biological and molecular eventsoccurring in different organisms. A variety of techniques andsoftware tools have been developed to enable easier and morerapid means of exploring the genetic information. LÄS MER

7. 10. Approaches to differential gene expression analysis in atherosclerosis

   Författare :Tove Andersson; KTH; []
   Nyckelord :representational difference analysis; gene expression profiling; microarray analysis; atherosclerosis; foam cell formation;

   Sammanfattning : Today’s rapid development of powerful tools for geneexpression analysis provides unprecedented resources forelucidating complex molecular events.The objective of this workhas been to apply, combine andevaluate tools for analysis of differential gene expressionusing atherosclerosis as a model system. LÄS MER