Sökning: "gene duplications"

Visar resultat 11 - 15 av 81 avhandlingar innehållade orden gene duplications.

  1. 11. Evolution and Pharmacology of Neuropeptide Y Receptors, Implications for vertebrate genome duplications

    Författare :Robert Fredriksson; Susanne Holmgren; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurosciences; Evolution; tetraploidizations; G-protein coupled receptor; neuropeptide Y; zebrafish; chicken; rainbow trout; lamprey; genome duplications; peptide YY; pancreatic polypeptide; Neurovetenskap; Neurology; Neurologi; medicinsk farmakologi; Medical Pharmacology;

    Sammanfattning : The Y receptors comprise a family of evolutionarily related receptors belonging to the superfamily of G-protein coupled receptors (GPCR). Their natural ligands are in mammals neuropeptide Y (NPY), peptide YY (PYY) and pancreatic polypeptide (PP). LÄS MER

  3. 12. Evolutionary Genomics of Nematode-Trapping Fungi

    Författare :Tejashwari Meerupati; MEMEG; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nematode-trapping fungi; Comparative Genomics; Comparative Transcriptomics; Differential gene expression; Gene duplication; Parasitism; Protein family expansion.;

    Sammanfattning : Nematode-trapping fungi are ubiquitous, soil-living organisms with the ability to infect and kill nematodes. These fungi have developed specialized infection structures for the capture of nematodes. LÄS MER

  4. 13. Defining human adaptive immune gene diversity

    Författare :Sanjana Narang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The lymphocytes (B and T cells) of the adaptive immune system undergo variable (V), diversity (D), and junctional (J) gene recombination, resulting in highly diverse antigen receptor repertoires capable of recognizing a wide variety of invading pathogens. The B cell receptor (BCR) contains two identical heavy and light chains. LÄS MER

  5. 14. Reconciling gene family evolution and species evolution

    Författare :Joel Sjöstrand; Jens Lagergren; Nicolas Lartillot; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Computational biology; Bioinformatics; Phylogenetics; Phylogenomics; Comparative genomics; Evolutionary biology; datalogi; Computer Science;

    Sammanfattning : Species evolution can often be adequately described with a phylogenetic tree. Interestingly, this is the case also for the evolution of homologous genes; a gene in an ancestral species may – through gene duplication, gene loss, lateral gene transfer (LGT), and speciation events – give rise to a gene family distributed across contemporaneous species. LÄS MER

  7. 15. The Gene Repertoire of G protein-coupled Receptors : New Genes, Phylogeny, and Evolution

    Författare :Þóra Kristín Bjarnadóttir; Helgi B. Schiöth; Robert Fredriksson; Kurt Kristiansen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacology; Bioinformatics; Evolution; GPCR; Phylogeny; Farmakologi; Pharmacological research; Farmakologisk forskning;

    Sammanfattning : The superfamily of G protein-coupled receptors (GPCRs) is one of the largest protein families of mammalian genomes and can be divided into five main families; Glutamate, Rhodopsin, Adhesion, Frizzled, and Secretin. GPCRs participate in most major physiological functions, contributing to the fact that they are important targets in drug discovery. LÄS MER