Sökning: "gene amplification"
Visar resultat 16 - 20 av 225 avhandlingar innehållade orden gene amplification.
16. Transcriptome and Proteome Analysis using Signature Tags
Sammanfattning : With the full sequence of the human genome now available, anexciting era in biomedical research has started. The sequenceprovides information about all our genes and greatly increasesthe scope to compare genetic activities in different cells, toanalyze genetic variation between individuals and betweendifferent species and, most importantly, to investigatesystematically the whole genome in a gene-by-gene manner, andthus increase our understanding of gene function. LÄS MER
17. Multi-Resistance Plasmids : Fitness Costs, Dynamics and Evolution
Sammanfattning : Antibiotic resistance is an escalating problem, not only due to less desirable treatment options and outcome, but also due to the economic burden to health care caused by resistant pathogens. Since the process of developing new antibiotics is slow, we need to carefully consider the usage of the antibiotics still available. LÄS MER
18. Molecular Characterization of Genomic Amplifications in Pancreatic Cancer
Sammanfattning : Pancreatic cancer includes multiple histologic subtypes that show large differences in their clinical and biological characteristics. Despite this diversity, more than 85% of the neoplasms in the organ are malignant ductal adenocarcinomas, which are the focus of the present thesis. LÄS MER
19. Studies of PLAG1 and HMGIC fusion oncogenes in human tumors
Sammanfattning : .... LÄS MER
20. Hypoxic gene regulation and oncogenic pathways in neuroblastoma
Sammanfattning : Neuroblastoma patients show remarkable clinical heterogeneity, with courses ranging from spontaneous regression to fatal tumor progression despite intense multi-modal treatment. Previous studies have shown that hypoxia pushes neuroblastoma cells towards a more immature phenotype, which correlates to aggressive disease. LÄS MER