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Visar resultat 1 - 5 av 6 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Anxiety among Adolescents : Measurement, Clinical Characteristics, and Influences of Parenting and Genetics

   Författare :Susanne Olofsdotter; K.W. Nilsson; Tomas Furmark; Mats Humble; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Adolescent; anxiety; assessment; prevalence; comorbidity; parenting; oxytocin; gene–environment interaction; differential susceptibility; Child and Youth Psychiatry; Barn- och ungdomspsykiatri;

   Sammanfattning : Anxiety is the most commonly reported mental health problem among adolescents. Still, many adolescents in need of treatment are not detected and the clinical characteristics and etiological pathways of adolescent anxiety are under-researched topics. LÄS MER

3. 2. Predictors of Alcohol Misuse : Role of MAOA Genotype, Methylation, Transcription, and Negative and Positive Environmental factors

   Författare :Megha Bendre; Kent Nilsson; Erika Comasco; Ingrid Nylander; Mia Ericson; Uppsala universitet; []
   Nyckelord :Alcohol; AUD; MAOA; methylation; expression; early-life stress; maltreatment; parent–child relationship; gene–environment interactions.; Medicinsk vetenskap; Medical Science;

   Sammanfattning : Alcohol misuse is a risk factor for alcohol use disorder (AUD). Gene-environment interactions contribute to the risk or resilience for AUD. A functional polymorphism in the promoter of the monoamine oxidase A gene (MAOA-uVNTR), in interaction with negative environment (Eneg), is associated with alcohol misuse and AUD. LÄS MER

4. 3. Depressive Symptoms Among Adolescents and Young Adults : Psychometrics and the Influence of Family Environment, and Candidate Gene–environment Interactions

   Författare :Rebecka Keijser; Cecilia Åslund; Susanne Olofsdotter; Kent W. Nilsson; Mats Humble; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diathesis stress; differential susceptibility; early life stress; FKBP5; OXTR; parenting;

   Sammanfattning : The overall aims of this thesis were to evaluate the psychometric properties of a questionnaire designed to evaluate parenting styles, and to study how depressive symptoms among adolescents and young adults may vary depending on the family environment and candidate gene–environment interaction (cG×E).The study sample consisted of participants (born during 1997 or 1999), and their caregivers from the Survey of Adolescent Life in Västmanland Cohort Study. LÄS MER

5. 4. Genetic studies on childhood asthma and allergy : role of interactions

   Författare :Erik Melén; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Air pollution; asthma; allergy; BAMSE; child; environment; epistasis; GPR-A; genetics; haplotype; heredity; interaction; polymorphism; wheezing;

   Sammanfattning : The occurrence of asthma and allergic diseases is influenced by inherited and environmental factors, and symptoms of asthma and allergy usually begin in early childhood. The overall aim with this thesis was to study the role of genetic factors for the development of childhood asthma and allergy, and to evaluate potential interaction between genetic and environmental factors. LÄS MER

7. 5. Gene-environment interactions in rheumatoid arthritis : quantification and characterization of contributing factors

   Författare :Xia Jiang; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory disease characterised by persistent synovitis, systemic inflammation and autoantibodies. RA has a complex aetiology with the involvement of genetic factors and environmental triggers, and their interactions. LÄS MER